Sugi Predict

Sugi Predict / Compounds / SCHEMBL7175131

SCHEMBL7175131

SCHEMBL7175131

Cc1cccc(Cl)c1C(=O)P(=O)(C(=O)c1ccccc1)c1c(C)cccc1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ITGB1 P05556 4/20 0.40
▸ ITGA4 P13612 4/20 0.40
▸ ITGB7 P26010 3/20 0.40
▸ FABP3 P05413 1/20 0.40
▸ FABP4 P15090 1/20 0.40
▸ TYK2 P29597 1/20 0.37
▸ NR1H4 Q96RI1 1/20 0.36
▸ LMNA P02545 3/20 0.35
▸ MAPT P10636 3/20 0.35
▸ MEN1 O00255 2/20 0.35
▸ KMT2A Q03164 2/20 0.35
▸ HTT P42858 2/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.35
▸ KAT6A Q92794 1/20 0.35
▸ ITGA2 P17301 1/20 0.35
▸ CYP2A6 P11509 1/20 0.35
▸ ITGB2 P05107 1/20 0.35
▸ ICAM1 P05362 1/20 0.35
▸ ITGAL P20701 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7184560 0.96 ITGB1 (0.39) ITGB1ITGA4ITGB7FABP3FABP4
SCHEMBL7180582 0.91 NR1H4 (0.40) NR1H4MAPTMEN1KMT2AHTT
SCHEMBL7185192 0.89 FABP4 (0.41) FABP4LMNAMAPTKMT2AHTT
SCHEMBL7182217 0.84 MAPT (0.39) FABP3FABP4TYK2LMNAMAPT
SCHEMBL7182450 0.84 FABP3 (0.39) FABP3FABP4TYK2LMNAMAPT
SCHEMBL7190151 0.84 SMN1; SMN2 (0.40) NR1H4LMNAMAPTKMT2AAPAF1
SCHEMBL7190527 0.82 ATM (0.41) FABP3LMNAMAPTKMT2AHTT
SCHEMBL7181262 0.82 NR1H4 (0.38) NR1H4LMNAMAPTMEN1KMT2A
SCHEMBL7188688 0.81 TYK2 (0.38) ITGB1ITGA4FABP3FABP4TYK2
SCHEMBL7175134 0.81 FABP3 (0.42) ITGB1ITGA4ITGB7FABP3FABP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 ITGB1 2786/4885ITGA4 3521/4885ITGB7 2326/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 ITGB1 3321/4885ITGA4 3643/4885ITGB7 3119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.