Sugi Predict

Sugi Predict / Compounds / SCHEMBL7180582

SCHEMBL7180582

SCHEMBL7180582

Cc1cccc(C)c1C(=O)P(=O)(C(=O)c1ccccc1)c1c(C)cccc1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ NR1H4 Q96RI1 2/20 0.40
▸ FFAR1 O14842 1/20 0.37
▸ POLB P06746 2/20 0.36
▸ MYC P01106 1/20 0.36
▸ HPGD P15428 1/20 0.36
▸ L3MBTL1 Q9Y468 2/20 0.35
▸ CNR2 P34972 2/20 0.35
▸ ALDH1A1 P00352 3/20 0.35
▸ MAPT P10636 3/20 0.35
▸ KDM4E B2RXH2 1/20 0.35
▸ NPC1 O15118 1/20 0.35
▸ RAB9A P51151 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ SMYD2 Q9NRG4 1/20 0.35
▸ MEN1 O00255 2/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ CTDSP1 Q9GZU7 1/20 0.34
▸ EPHX1 P07099 1/20 0.34
▸ HSP90AA1 P07900 1/20 0.34
▸ HSP90AB1 P08238 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7190151 0.92 SMN1; SMN2 (0.40) NR1H4FFAR1POLBHPGDL3MBTL1
SCHEMBL7175131 0.91 ITGB1 (0.40) NR1H4HPGDL3MBTL1ALDH1A1MAPT
SCHEMBL7184560 0.90 ITGB1 (0.39) NR1H4FFAR1HPGDL3MBTL1ALDH1A1
SCHEMBL7184791 0.89 RXRA (0.41) NR1H4FFAR1L3MBTL1CNR2ALDH1A1
SCHEMBL7190527 0.87 ATM (0.41) L3MBTL1CNR2ALDH1A1MAPTKDM4E
SCHEMBL7181262 0.87 NR1H4 (0.38) NR1H4FFAR1POLBL3MBTL1CNR2
SCHEMBL7182455 0.86 ALDH1A1 (0.38) NR1H4ALDH1A1MAPTGAANPSR1
SCHEMBL7189406 0.84 HTT (0.42) POLBL3MBTL1CNR2ALDH1A1MAPT
SCHEMBL7185192 0.83 FABP4 (0.41) L3MBTL1ALDH1A1MAPTKDM4ENPC1
SCHEMBL7182450 0.82 FABP3 (0.39) POLBHPGDALDH1A1MAPTSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 NR1H4 105/4885FFAR1 671/4885POLB 2322/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 NR1H4 149/4885FFAR1 711/4885POLB 2993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.