SCHEMBL7175227

SCHEMBL7175227

FC(F)(F)c1cccc(NC(=S)Nc2cccc(C(F)(F)F)c2)c1

nearest known ligand 0.86

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.86
ALDH1A1 P00352 6/20 0.86
NPSR1 Q6W5P4 5/20 0.86
GAA P10253 5/20 0.86
TDP1 Q9NUW8 3/20 0.86
MEN1 O00255 4/20 0.81
KMT2A Q03164 4/20 0.81
SMN1; SMN2 Q16637 3/20 0.81
CYP1A2 P05177 2/20 0.81
CYP3A4 P08684 2/20 0.81
CYP2D6 P10635 2/20 0.81
CYP2C19 P33261 2/20 0.81
IDO1 P14902 1/20 0.81
L3MBTL1 Q9Y468 3/20 0.79
KDM4E B2RXH2 2/20 0.79
LMNA P02545 4/20 0.69
XBP1 P17861 2/20 0.68
POLB P06746 1/20 0.68
CYP2C9 P11712 1/20 0.68
TP53 P04637 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22567938 0.95 MAPT (0.78) MAPTALDH1A1NPSR1GAATDP1
SCHEMBL22567749 0.95 MAPT (0.78) MAPTALDH1A1NPSR1GAATDP1
SCHEMBL22024982 0.92 SMN1; SMN2 (0.75) MAPTALDH1A1NPSR1GAATDP1
SCHEMBL24169274 0.90 MAPT (1.00) MAPTALDH1A1NPSR1GAATDP1
SCHEMBL30387868 0.90 MAPT (1.00) MAPTALDH1A1NPSR1GAATDP1
SCHEMBL22065211 0.90 MAPT (0.72) MAPTALDH1A1NPSR1GAATDP1
SCHEMBL2467470 0.90 IDO1 (1.00) MAPTALDH1A1NPSR1GAATDP1
SCHEMBL12412637 0.90 ALDH1A1 (0.76) MAPTALDH1A1NPSR1GAATDP1
SCHEMBL6816145 0.89 IDO1 (0.70) MAPTALDH1A1NPSR1GAATDP1
SCHEMBL7986700 0.89 ALDH1A1 (0.69) MAPTALDH1A1NPSR1GAATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4599630-A USING LEUCO DYES WHICH FORM TWO DIFFERENT COLORS WHEN HEATED AT DIFFERENT TEMPERATURES RICOH COMPANY, LTD. (JP) 1986-07-08 US claimed
JP-59136288-A None JP disclosed
CN-102276548-B Method for synthesizing 2-iminothiazolidine-4-one and derivatives thereof UNIV XI AN JIAOTONG 2013-07-31 CN disclosed
US-6579829-B2 Aromatic sulfonamide compound MITSUI CHEMICALS, INC. (JP) 2003-06-17 US disclosed
EP-0664292-B1 A phtalide compound and a near infrared absorber and a recording material each comprising the same compound YAMAMOTO CHEMICALS INC (JP) 2002-06-19 EP disclosed
US-20010036903-A1 Developer composition and heat sensitive recording material MITSUI CHEMICALS, INC. (JP) 2001-11-01 US disclosed
EP-1138517-A2 Developer composition and heat sensitive recording material Mitsui Chemicals, Inc. (JP) 2001-10-04 EP disclosed
US-5627287-A COLORLESS YAMAMOTO CHEMICALS, INC. (JP) 1997-05-06 US disclosed
EP-0664292-A1 A phtalide compound and a near infrared absorber and a recording material each comprising the same compound YAMAMOTO CHEMICALS, INC. (JP) 1995-07-26 EP disclosed
US-5234798-A Show previously hidden image on exposure to radiant energy DITTLER BROTHERS, INCORPORATED (US) 1993-08-10 US disclosed
US-4855279-A SENSITIZER EXCELLENT IN THERMAL RESPONSE PROPERTIES AND SENSI TIVITY MITSUBISHI PAPER MILLS, LIMITED (JP) 1989-08-08 US disclosed
US-4837197-A SPECIAL SENSITIIZER EXCELLENT IN THERMAL RESPONSE MITSUBISHI PAPER MILLS, LTD. (JP) 1989-06-06 US disclosed
US-4764501-A COLORLESS DYE PRECURSOR, COLOR DEVELOPER AND SENSITIZER; EXCELLENT THERMAL RESPONSE MITSUBISHI PAPER MILLS, LTD. (JP) 1988-08-16 US disclosed
US-4755831-A Multi-layer full-color thermosensitive sheet recording method RICOH COMPANY, LTD. (JP) 1988-07-05 US disclosed
US-4665410-A THERMOGRAPHY RICOH COMPANY, LTD. (JP) 1987-05-12 US disclosed
US-4663641-A LEUCO DYES; DECOLORIZING AGENTS, PIPERAZINE COMPOUND; AMIDES AND TERTIARY AMINES RICOH COMPANY, LTD. (JP) 1987-05-05 US disclosed
US-4620204-A MILTILAYER-SUPPORT, HIGH TEMPERATURE THERMOSENSITIVE LAYER, VINYLIDENE CHLORIDE INTERMEDIATE LAYER AND LOW TEMPERATURE COLOR FORMING LAYER RICOH COMPANY, LTD. (JP) 1986-10-28 US disclosed
US-4613878-A DECOLORIZING AGENT COMPRISING AROMATIC DIAMIDE OR PIPERAZINE DERIVATIVE, HAVING TWO ACYLAMINO GROUPS RICOH COMPANY, LTD. (JP) 1986-09-23 US disclosed
JP-S59136288-A HEAT-SENSITIVE RECORDING MATERIAL RICOH CO LTD 1984-08-04 JP disclosed