Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.69 |
| ▸ | MAPT | P10636 | 8/20 | 0.69 |
| ▸ | GAA | P10253 | 7/20 | 0.69 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | IDO1 | P14902 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | XBP1 | P17861 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175227 | 0.89 | MAPT (0.86) | ALDH1A1MAPTGAANPSR1TDP1 | |
| SCHEMBL22567938 | 0.87 | MAPT (0.78) | ALDH1A1MAPTGAANPSR1TDP1 | |
| SCHEMBL7569356 | 0.86 | MAPT (0.57) | ALDH1A1MAPTGAANPSR1TDP1 | |
| SCHEMBL22024982 | 0.84 | SMN1; SMN2 (0.75) | ALDH1A1MAPTGAANPSR1TDP1 | |
| SCHEMBL22567749 | 0.84 | MAPT (0.78) | ALDH1A1MAPTGAANPSR1TDP1 | |
| SCHEMBL11007615 | 0.82 | MAPT (0.69) | ALDH1A1MAPTGAANPSR1TDP1 | |
| SCHEMBL6816145 | 0.82 | IDO1 (0.70) | ALDH1A1MAPTGAANPSR1TDP1 | |
| SCHEMBL24169274 | 0.80 | MAPT (1.00) | ALDH1A1MAPTGAANPSR1TDP1 | |
| SCHEMBL22065211 | 0.80 | MAPT (0.72) | ALDH1A1MAPTGAANPSR1TDP1 | |
| SCHEMBL30387868 | 0.80 | MAPT (1.00) | ALDH1A1MAPTGAANPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6271236-B1 | PHENYL UREAS/THIOUREAS AS INHIBITORS OF INOSINE MONOPHOSPHATE DEHYDROGENASE ENZYME, USEFUL IN TREATING HUMAN CYTOMEGALOVIRUS, HERPES SIMPLEX VIRUSES, EPSTEIN-BARR VIRUS, AND VARICELLA-ZOSTER VIRUS | WYETH | 2001-08-07 | — | — | US | disclosed |