Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 3/20 | 0.52 |
| ▸ | TOP1 | P11387 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7175238 | 1.00 | LTB4R (0.52) | LTB4RTOP1TSHRCYP2D6CYP2C9 | |
| SCHEMBL15587062 | 0.87 | LTB4R (0.59) | LTB4RTSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL8826605 | 0.87 | LTB4R (0.59) | LTB4RTSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL3254192 | 0.87 | LTB4R (0.59) | LTB4RTSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7385392 | 0.85 | LTB4R (0.66) | LTB4RTSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17027841 | 0.83 | LTB4R (0.68) | LTB4RTSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6971015 | 0.83 | LTB4R (0.68) | LTB4RTSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL6344592 | 0.83 | LTB4R (0.68) | LTB4RTSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL17027837 | 0.83 | LTB4R (0.68) | LTB4RTSHRCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL7175350 | 0.82 | GRIK1 (0.51) | TOP1SMN1; SMN2MAPK1GRIK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1241941-B1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | UNIV NORTH CAROLINA STATE (US) | 2003-06-18 | — | — | EP | claimed |