Sugi Predict

Sugi Predict / Compounds / SCHEMBL7175306

SCHEMBL7175306

SCHEMBL7175306

Cc1cccc(C)c1C(=O)c1ccccc1[P](=O)C(=O)c1c(C(F)(F)F)cccc1C(F)(F)F

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ TAS2R14 Q9NYV8 3/20 0.39
▸ ALDH1A1 P00352 2/20 0.38
▸ ALOX12 P18054 1/20 0.38
▸ RORC P51449 5/20 0.38
▸ GAA P10253 2/20 0.37
▸ LMNA P02545 1/20 0.37
▸ SLC6A2 P23975 1/20 0.35
▸ SLC6A4 P31645 1/20 0.35
▸ KCNK3 O14649 1/20 0.34
▸ KCNK9 Q9NPC2 1/20 0.34
▸ P2RX7 Q99572 1/20 0.34
▸ GPBAR1 Q8TDU6 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CNR2 P34972 1/20 0.34
▸ KDM4E B2RXH2 1/20 0.34
▸ ATM Q13315 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7180621 0.96 TAS2R14 (0.38) TAS2R14ALDH1A1ALOX12RORCGAA
SCHEMBL7186793 0.91 KCNK3 (0.37) TAS2R14ALDH1A1ALOX12RORCGAA
SCHEMBL7180491 0.91 TAS2R14 (0.39) TAS2R14ALDH1A1ALOX12RORCGAA
SCHEMBL7181426 0.90 TAS2R14 (0.41) TAS2R14ALDH1A1ALOX12RORCGAA
SCHEMBL7180933 0.89 TAS2R14 (0.39) TAS2R14ALDH1A1ALOX12RORCGAA
SCHEMBL7188665 0.88 MEN1 (0.38) TAS2R14ALDH1A1ALOX12RORCGAA
SCHEMBL7187550 0.87 TAS2R14 (0.38) TAS2R14ALDH1A1ALOX12RORCGAA
SCHEMBL7730584 0.86 TAS2R14 (0.37) TAS2R14ALDH1A1ALOX12RORCGAA
SCHEMBL7182517 0.85 F2R (0.36) TAS2R14RORCGAALMNAKCNK3
SCHEMBL7185610 0.84 RORC (0.46) RORCCYP3A4CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 TAS2R14 2184/4885ALDH1A1 3416/4885ALOX12 1332/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 TAS2R14 2410/4885ALDH1A1 3984/4885ALOX12 899/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.