Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4511528 | 0.72 | MAP4K4 (0.33) | PDE10A | |
| SCHEMBL4478891 | 0.72 | ALDH1A1 (0.34) | PDE10AALDH1A1 | |
| SCHEMBL6201153 | 0.71 | PDE10A (0.36) | PDE10AALDH1A1 | |
| SCHEMBL5769043 | 0.68 | ALDH1A1 (0.38) | ALDH1A1 | |
| SCHEMBL12962760 | 0.67 | PDE10A (0.31) | PDE10A | |
| SCHEMBL6202914 | 0.67 | PDE10A (0.33) | PDE10A | |
| SCHEMBL23143322 | 0.64 | DYRK1A (0.47) | ALDH1A1 | |
| Hydrochloric Acid SCHEMBL1605985 | 0.64 | PDE10A (0.32) | PDE10A | |
| SCHEMBL6203248 | 0.64 | KDM4E (0.32) | PDE10AALDH1A1 | |
| SCHEMBL717559 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8268835-B2 | Inhibitors of hepatitis C virus RNA-dependent RNA polymerase, and compositions and treatments using the same | PFIZER INC. (US) | 2012-09-18 | — | — | US | disclosed |
| US-20090281122-A1 | Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase, and Compositions and Treatments Using the Same | PFIZER INC | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090281122-A1 | Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase, and Compositions and Treatments Using the Same | RNASE1, GTF3C4, POLRMT | PDE10A 3125/4885ALDH1A1 792/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.