Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6816683 | 0.80 | ALDH1A1 (0.52) | KMT2ANPSR1MEN1HTTRAB9A | |
| SCHEMBL6816676 | 0.80 | ALDH1A1 (0.46) | KMT2ANPSR1MEN1ALDH1A1KDM4E | |
| SCHEMBL6815053 | 0.79 | MAPT (0.60) | KMT2ANPSR1MEN1RAB9ANPC1 | |
| SCHEMBL7162313 | 0.79 | MEN1 (0.86) | KMT2ANPSR1MEN1HTTUSP2 | |
| SCHEMBL7778713 | 0.76 | RAB9A (0.67) | KMT2ANPSR1MEN1HTTRAB9A | |
| SCHEMBL7848327 | 0.74 | RAB9A (0.69) | KMT2AMEN1RAB9ANPC1CASP3 | |
| SCHEMBL7157873 | 0.74 | NPSR1 (0.55) | KMT2ANPSR1MEN1HTTUSP2 | |
| SCHEMBL7163720 | 0.74 | MEN1 (0.60) | KMT2ANPSR1MEN1HTTUSP2 | |
| SCHEMBL7162970 | 0.74 | MYC (0.65) | KMT2ANPSR1MEN1HTTUSP2 | |
| SCHEMBL7848400 | 0.73 | RAB9A (0.66) | KMT2ANPSR1MEN1HTTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555561-B2 | N-(5-((((5-Chloro-2,4-dimethoxyphenyl)amino)thioxomethyl)-amino)-2 -pyridinyl)-2-methylbenzamide, for example; inhibiting replication of a herpes virus | WYETH | 2003-04-29 | — | — | US | disclosed |