Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 5/20 | 0.65 |
| ▸ | LDHB | P07195 | 5/20 | 0.65 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7186222 | 0.85 | LDHA (0.62) | LDHALDHBHSD17B10MEN1KMT2A | |
| SCHEMBL7176330 | 0.80 | LDHA (0.59) | LDHALDHBALBHSD17B10MEN1 | |
| SCHEMBL7174623 | 0.79 | LDHA (1.00) | LDHALDHBALBHSD17B10TSHR | |
| SCHEMBL7180813 | 0.77 | LDHA (0.70) | LDHALDHBMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL8460263 | 0.75 | LDHA (0.65) | LDHALDHBALBHSD17B10MEN1 | |
| SCHEMBL9627592 | 0.75 | ABCB11 (0.51) | LDHALDHBHSD17B10TSHRMEN1 | |
| SCHEMBL9657958 | 0.73 | LDHA (0.48) | LDHALDHBHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL9657719 | 0.71 | LDHA (0.49) | LDHALDHBHSD17B10TSHRMEN1 | |
| SCHEMBL7176551 | 0.71 | LDHA (0.56) | LDHALDHBPPARA | |
| SCHEMBL9629355 | 0.70 | LDHA (0.48) | LDHALDHBHSD17B10TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0980350-A4 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | UNIV NEW MEXICO (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6124498-A | Hydroxynaphthoic acids and derivatives | UNIVERSITY OF NEW MEXICO (US) | 2000-09-26 | — | — | US | disclosed |
| EP-0980350-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | The University of New Mexico (US) | 2000-02-23 | — | — | EP | disclosed |
| WO-1998049130-A2 | HYDROXYNAPHTHOIC ACIDS AND DERIVATIVES | THE UNIVERSITY OF NEW MEXICO (US) | 1998-11-05 | — | — | WO | disclosed |