Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A1 | P22736 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CTH | P32929 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7181267 | 0.96 | NR4A1 (0.36) | NR4A1KDM4ENPSR1TDP1MAOA | |
| Hydrochloric Acid SCHEMBL7179444 | 0.96 | NR4A1 (0.36) | NR4A1KDM4ENPSR1TDP1MAOA | |
| Hydrochloric Acid SCHEMBL7171706 | 0.96 | NR4A1 (0.36) | NR4A1KDM4ENPSR1TDP1MAOA | |
| Hydrochloric Acid SCHEMBL7177279 | 0.96 | NR4A1 (0.36) | NR4A1KDM4ENPSR1TDP1MAOA | |
| Hydrochloric Acid SCHEMBL7174410 | 0.96 | NR4A1 (0.36) | NR4A1KDM4ENPSR1TDP1MAOA | |
| Hydrochloric Acid SCHEMBL7176698 | 0.96 | NR4A1 (0.36) | NR4A1KDM4ENPSR1TDP1MAOA | |
| SCHEMBL5589354 | 0.96 | CTH (0.36) | NR4A1KDM4ENPSR1TDP1MAOA | |
| SCHEMBL5589346 | 0.96 | CTH (0.36) | NR4A1KDM4ENPSR1TDP1MAOA | |
| SCHEMBL5587761 | 0.94 | CTH (0.35) | NR4A1KDM4ENPSR1TDP1MAOA | |
| SCHEMBL5693787 | 0.94 | CTH (0.35) | NR4A1KDM4ENPSR1TDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |