Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 10/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7185083 | 0.97 | CYP3A4 (0.36) | CYP3A4CYP2D6CYP2C9TLR8NOS2 | |
| Hydrochloric Acid SCHEMBL7179597 | 0.97 | CYP3A4 (0.36) | CYP3A4CYP2D6CYP2C9TLR8NOS2 | |
| Hydrochloric Acid SCHEMBL7179236 | 0.97 | CYP3A4 (0.36) | CYP3A4CYP2D6CYP2C9TLR8NOS2 | |
| Hydrochloric Acid SCHEMBL7181720 | 0.97 | CYP3A4 (0.36) | CYP3A4CYP2D6CYP2C9TLR8NOS2 | |
| Hydrochloric Acid SCHEMBL7177068 | 0.97 | CYP3A4 (0.36) | CYP3A4CYP2D6CYP2C9TLR8NOS2 | |
| Hydrochloric Acid SCHEMBL7175687 | 0.92 | GRM5 (0.35) | NOS2 | |
| Hydrochloric Acid SCHEMBL7177566 | 0.90 | NOS2 (0.36) | CYP3A4CYP2D6CYP2C9TLR8NOS2 | |
| Hydrochloric Acid SCHEMBL7177962 | 0.89 | TLR8 (0.34) | CYP3A4CYP2D6CYP2C9TLR8NOS2 | |
| Hydrochloric Acid SCHEMBL7179139 | 0.89 | GRM5 (0.35) | NOS2KCNH2 | |
| Hydrochloric Acid SCHEMBL7177587 | 0.89 | GRM5 (0.35) | NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |