Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 5/20 | 0.50 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.45 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 2/20 | 0.40 |
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.35 |
| ▸ | FEN1 | P39748 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3818506 | 0.77 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1ALDH1A1ALOX15 | |
| SCHEMBL17420795 | 0.77 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1ALDH1A1ALOX15 | |
| SCHEMBL31414989 | 0.77 | KCNN4 (0.52) | KCNN4KCNE1KCNQ1ALDH1A1ALOX15 | |
| SCHEMBL30501782 | 0.75 | KCNN4 (0.50) | KCNN4KCNE1KCNQ1ALDH1A1ALOX15 | |
| SCHEMBL1239901 | 0.75 | KCNN4 (0.50) | KCNN4KCNE1KCNQ1ALDH1A1ALOX15 | |
| SCHEMBL31560841 | 0.73 | KCNN4 (0.49) | KCNN4KCNE1KCNQ1ALDH1A1CES2 | |
| SCHEMBL8315982 | 0.73 | KCNN4 (0.49) | KCNN4KCNE1KCNQ1ALDH1A1ALOX15 | |
| SCHEMBL6335614 | 0.73 | KCNN4 (0.49) | KCNN4KCNE1KCNQ1CYP1A2ALDH1A1 | |
| SCHEMBL1822203 | 0.73 | KCNN4 (0.49) | KCNN4KCNE1KCNQ1ALDH1A1ALOX15 | |
| SCHEMBL6904757 | 0.73 | POLB (0.44) | KCNN4CYP1A2ALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0984919-B1 | PROCESS FOR THE PREPARATION OF ARYLMALONATES | BASF AG (DE) | 2003-01-22 | — | — | EP | disclosed |
| EP-0984919-A4 | PROCESS FOR THE PREPARATION OF ARYLMALONATES | AMERICAN CYANAMID CO (US) | 2000-07-12 | — | — | EP | disclosed |
| EP-0984919-A1 | PROCESS FOR THE PREPARATION OF ARYLMALONATES | AMERICAN CYANAMID COMPANY (US) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998041496-A1 | PROCESS FOR THE PREPARATION OF ARYLMALONATES | AMERICAN CYANAMID COMPANY (US) | 1998-09-24 | — | — | WO | disclosed |
| US-5756815-A | DEHALOGENATION, CARBOXYLATION WITH MAGNESIUM AND DIALKYL CARBONATE OR AN ALKYL CHLOROFORMATE FOR INHIBITING BY-PRODUCT | AMERICAN CYANAMID COMPANY (US) | 1998-05-26 | — | — | US | disclosed |