SCHEMBL7178450

SCHEMBL7178450

CCC(OC(=O)C=CC(=O)O)[Si]1(C)CCC(C)(C)O[Si]1(C)C

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8736053 0.95
SCHEMBL9239075 0.90 KEAP1 (0.32) HCAR2
SCHEMBL9243501 0.89 HCAR2 (0.35) HCAR2
SCHEMBL9576515 0.87 PRKCA (0.31)
SCHEMBL9283994 0.87
SCHEMBL7179700 0.84 HCAR2 (0.33) HCAR2
SCHEMBL9241061 0.83 HCAR2 (0.42) HCAR2
SCHEMBL10784040 0.83 HCAR2 (0.36) HCAR2
SCHEMBL10771024 0.78 HCAR2 (0.32) HCAR2
SCHEMBL8736690 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0722110-B1 Water absorptive soft contact lens MENICON CO LTD (JP) 2003-09-17 EP disclosed
EP-0729041-B1 Water-Absorptive soft contact lens MENICON CO LTD (JP) 2001-11-28 EP disclosed
US-5741830-A COPOLYMER OF A FLUORINE CONTAINING STYRENE DERIVATIVE AND N,N-DIMETHYL(METH)ACRYLAMIDE MENICON CO., LTD. (JP) 1998-04-21 US disclosed
EP-0729041-A2 Water-Absorptive soft contact lens Menicon Co., Ltd. (JP) 1996-08-28 EP disclosed
EP-0722110-A2 Water absorptive soft contact lens Menicon Co., Ltd. (JP) 1996-07-17 EP disclosed
EP-0244835-A2 Langmuir-Blodgett ultrathin membrane of polyfumurate NIPPON OIL AND FATS COMPANY, LIMITED (JP) 1987-11-11 EP disclosed