Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | KRAS | P01116 | 1/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 9/20 | 0.48 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.43 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.41 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.41 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7178910 | 1.00 | CTSL (0.51) | CTSLCTSBCA1CA2KRAS | |
| SCHEMBL7180300 | 0.92 | PTPN1 (0.54) | CTSLCTSBPTPN1ABCG2CAPN1 | |
| SCHEMBL7180303 | 0.92 | PTPN1 (0.54) | CTSLCTSBPTPN1ABCG2CAPN1 | |
| SCHEMBL7186754 | 0.89 | CTSL (0.44) | CTSLCTSBCA1CA2KRAS | |
| SCHEMBL7186749 | 0.89 | CTSL (0.44) | CTSLCTSBCA1CA2KRAS | |
| SCHEMBL7190096 | 0.89 | PTPN1 (0.44) | CTSLCTSBPTPN1ABCG2CAPN1 | |
| SCHEMBL7190102 | 0.89 | PTPN1 (0.44) | CTSLCTSBPTPN1ABCG2CAPN1 | |
| SCHEMBL7190370 | 0.89 | CTSL (0.43) | CTSLCTSBCA1CA2KRAS | |
| SCHEMBL7190368 | 0.89 | CTSL (0.43) | CTSLCTSBCA1CA2KRAS | |
| SCHEMBL7186544 | 0.88 | CTSL (0.43) | CTSLCTSBCA1CA2KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6603046-B1 | The invention is drawn to novel bis-aromatic a, beta -unsaturated ketones. The compounds are useful in the treatment and prophylaxis of diseases caused by parasites or bacteria. | LICA PHARMACEUTICALS A/S (DK) | 2003-08-05 | — | — | US | disclosed |
| EP-0634927-B1 | TREATMENT AND PROPHYLAXIS OF DISEASES CAUSED BY PARASITES, OR BACTERIA | LICA PHARMACEUTICALS AS (DK) | 2001-07-04 | — | — | EP | disclosed |
| US-5985935-A | PARASITICIDES OR BACTERICIDES | STATENS SERUMINSTITUT (DK) | 1999-11-16 | — | — | US | disclosed |