Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.31 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7178991 | 0.98 | GAA (0.33) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7185479 | 0.97 | GAA (0.33) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7175481 | 0.97 | GAA (0.33) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7173199 | 0.97 | GAA (0.33) | GAAMEN1KMT2AMAPK1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7176584 | 0.92 | — | — | |
| Hydrochloric Acid SCHEMBL7182780 | 0.91 | ALDH1A1 (0.30) | GAAMAPK1ALDH1A1HPGDPPARG | |
| Hydrochloric Acid SCHEMBL7173770 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL7184999 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL7176030 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL7171337 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |