SCHEMBL7179072

SCHEMBL7179072

CCC(CC)Cc1cc(O)ccc1Cl

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.43
CA12 O43570 1/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
CA14 Q9ULX7 1/20 0.39
ALOX15 P16050 2/20 0.39
ALOX12 P18054 1/20 0.39
ESR1 P03372 4/20 0.36
CYP1A2 P05177 2/20 0.35
CYP3A4 P08684 2/20 0.35
LMNA P02545 1/20 0.35
PGR P06401 1/20 0.35
CHRM2 P08172 1/20 0.35
ADORA3 P0DMS8 1/20 0.35
AR P10275 1/20 0.35
CYP2D6 P10635 1/20 0.35
MAPT P10636 1/20 0.35
CHRM1 P11229 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL365736 0.78 HSD17B10 (0.52) HSD17B10CA12CA1CA2CA7
SCHEMBL19025083 0.75 HSD17B10 (0.48) HSD17B10CA12CA1CA2CA7
SCHEMBL8738071 0.73 HSD17B10 (0.56) HSD17B10CA12CA1CA2CA7
SCHEMBL875312 0.73 ESR1 (0.43) HSD17B10ALOX15ALOX12ESR1SLC6A2
SCHEMBL21726735 0.72 IDO1 (0.46) LMNACHRM2SLC6A2SLC6A3
Benzene SCHEMBL631929 0.72 HSD17B10 (0.45) HSD17B10CA12CA1CA2CA7
SCHEMBL875816 0.72 TYR (0.61) HSD17B10CA12CA1CA2CA7
SCHEMBL8763525 0.72 ALOX15 (0.40) HSD17B10ALOX15ALOX12CYP3A4LMNA
SCHEMBL6131843 0.71 HSD17B10 (0.54) HSD17B10CA12CA1CA2CA7
SCHEMBL696050 0.71 HSD17B10 (0.54) HSD17B10CA12CA1CA2CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110087634-A Methods of providing oral care benefits 费丁制药联合股份有限公司 2019-08-02 CN disclosed
EP-1322738-A2 HARD SURFACE CLEANING AND DISINFECTING COMPOSITIONS Reckitt Benckiser Inc. (US) 2003-07-02 EP disclosed
WO-2002026268-A2 HARD SURFACE CLEANING AND DISINFECTING COMPOSITIONS RECKITT BENCKISER INC. (US) 2002-04-04 WO disclosed