Benzene

Benzene

SCHEMBL631929

CCCc1cc(O)ccc1Cl.c1ccccc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.45
PTPN1 P18031 1/20 0.43
PTPN11 Q06124 1/20 0.43
TYR P14679 2/20 0.43
ESR1 P03372 1/20 0.42
ESR2 Q92731 1/20 0.42
HSD17B3 P37058 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41
CA9 Q16790 1/20 0.41
CA14 Q9ULX7 1/20 0.41
MAPT P10636 2/20 0.41
ALOX5 P09917 2/20 0.41
MEN1 O00255 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19025083 0.96 HSD17B10 (0.48) HSD17B10PTPN1PTPN11TYRESR1
SCHEMBL875816 0.85 TYR (0.61) HSD17B10TYRESR1ESR2CA12
SCHEMBL28361071 0.81 ALOX5 (0.64) HSD17B10TYRESR1MAPTALOX5
SCHEMBL2222155 0.81 ALOX5 (0.64) HSD17B10TYRESR1MAPTALOX5
SCHEMBL9565680 0.80 TYR (0.50) HSD17B10TYRESR1ESR2HSD17B3
SCHEMBL365736 0.79 HSD17B10 (0.52) HSD17B10TYRESR1ESR2HSD17B3
SCHEMBL2471139 0.79 HSD17B3 (0.48) HSD17B10TYRESR1ESR2HSD17B3
SCHEMBL10825810 0.77 TYR (0.55) PTPN1PTPN11TYRESR1ESR2
SCHEMBL31613067 0.77 TYR (0.55) PTPN1PTPN11TYRESR1ESR2
SCHEMBL7494873 0.76 HSD17B10 (0.48) HSD17B10TYRESR1ESR2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 412 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090214606-A1 ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES CIBA SPECIALTY CHEMICALS CORP. 2009-08-27 US claimed
EP-1549731-B1 CLEANING AND DISINFECTING COMPOSITION RECKITT BENCKISER INC (US) 2008-12-17 EP claimed
EP-1879457-A1 ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES Ciba Specialty Chemicals Holding, Inc. (CH) 2008-01-23 EP claimed
US-20070231295-A1 Antimicrobial Silicon Oxide Flakes CIBA SPECIALTY CHEMICALS CORP. 2007-10-04 US claimed
EP-1755381-A2 ANTIMICROBIAL SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2007-02-28 EP claimed
WO-2006120135-A1 ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2006-11-16 WO claimed
US-20060093570-A1 Surface treatment RECKITT BENCKISER (UK) LIMITED (GB) 2006-05-04 US claimed
US-20060040847-A1 Hard surface treating compositions RECKITT BENCKISER INC. 2006-02-23 US claimed
US-20060034880-A1 Cleaning and disinfecting composition RECKITT BENCKISER INC (US) 2006-02-16 US claimed
WO-2005107456-A2 ANTIMICROBIAL SILICON OXIDE FLAKES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-11-17 WO claimed
US-20050233930-A1 Disinfectant cleaning compositions RECKITT BENCKISER INC. (US) 2005-10-20 US claimed
EP-1549731-A1 CLEANING AND DISINFECTING COMPOSITION Reckitt Benckiser Inc. (US) 2005-07-06 EP claimed
US-20050042266-A1 Cyanoacrylate compositions containing anti-microbial agent CLOSURE MEDICAL CORPORATION (US) 2005-02-24 US claimed
EP-1508601-A1 Cyanoacrylate compositions containing anti-microbial agent Closure Medical Corporation (US) 2005-02-23 EP claimed
WO-2004035724-A1 CLEANING AND DISINFECTING COMPOSITION RECKITT BENCKISER INC (US) 2004-04-29 WO claimed
US-12496344-B2 Biophotonic materials and uses thereof FLE INT S R L (IT) 2025-12-16 US disclosed
US-20250275534-A1 EFFERVESCENT GERMICIDAL COMPOSITIONS Reckitt & Colman (Overseas) Hygiene Home Limited (GB) 2025-09-04 US disclosed
WO-2000024858-A1 FABRIC COLOR CARE METHOD THE PROCTER & GAMBLE COMPANY (US) 2000-05-04 WO disclosed
WO-1999055953-A1 FABRIC WRINKLE CONTROL COMPOSITION AND METHOD THE PROCTER & GAMBLE COMPANY (US) 1999-11-04 WO disclosed
WO-1999055952-A1 FABRIC WRINKLE CONTROL COMPOSITION AND METHOD THE PROCTER & GAMBLE COMPANY (US) 1999-11-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250275534-A1 EFFERVESCENT GERMICIDAL COMPOSITIONS GSDMD, CASP3, CASP1 HSD17B10 2732/4885PTPN1 699/4885PTPN11 1297/4885
US-20060034880-A1 Cleaning and disinfecting composition APOBEC3G, APOBEC3C, APOBEC3B HSD17B10 3802/4885PTPN1 706/4885PTPN11 1334/4885
US-20050042266-A1 Cyanoacrylate compositions containing anti-microbial agent CLSPN, PCNA, CDC73 HSD17B10 3029/4885PTPN1 1120/4885PTPN11 1675/4885
US-20070231295-A1 Antimicrobial Silicon Oxide Flakes SIK2, SIK3, SIK1 HSD17B10 3334/4885PTPN1 1835/4885PTPN11 1310/4885
US-20090214606-A1 ANTIMICROBIAL POROUS SILICON OXIDE PARTICLES ORAI3, PRF1, THPO HSD17B10 4471/4885PTPN1 73/4885PTPN11 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.