Sugi Predict

Sugi Predict / Compounds / SCHEMBL7180141

SCHEMBL7180141

SCHEMBL7180141

Cc1cccc(C)c1C(=O)[P](=O)c1ccccc1C(=O)c1c(Cl)c(Cl)c(Cl)c(Cl)c1Cl

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 2/20 0.35
▸ LMNA P02545 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ RORC P51449 4/20 0.35
▸ CYP2C9 P11712 2/20 0.35
▸ MAPK13 O15264 3/20 0.34
▸ MAPK12 P53778 3/20 0.34
▸ MAPK11 Q15759 3/20 0.34
▸ MAPK14 Q16539 3/20 0.34
▸ KMT2A Q03164 2/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ CNR2 P34972 2/20 0.34
▸ ENPP3 O14638 1/20 0.33
▸ ALPL P05186 1/20 0.33
▸ XIAP P98170 1/20 0.33
▸ FLT1 P17948 1/20 0.33
▸ FLT4 P35916 1/20 0.33
▸ KDR P35968 1/20 0.33
▸ MYC P01106 1/20 0.33
▸ CNR1 P21554 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182191 0.91 MAPK13 (0.37) ALDH1A1LMNAGAARORCCYP2C9
SCHEMBL7186638 0.89 MEN1 (0.42) ALDH1A1LMNAGAAMAPK13MAPK12
SCHEMBL7174823 0.89 RORC (0.42) ALDH1A1LMNAGAARORCCYP2C9
SCHEMBL7184123 0.88 RORC (0.38) ALDH1A1LMNAGAARORCCYP2C9
SCHEMBL7179797 0.86 RORC (0.42) ALDH1A1LMNAGAARORCCYP2C9
SCHEMBL7179370 0.86 TSHR (0.38) ALDH1A1LMNAGAARORCCYP2C9
SCHEMBL7181446 0.86 GFER (0.36) ALDH1A1LMNAGAARORCCYP2C9
SCHEMBL7174655 0.85 RORC (0.37) ALDH1A1LMNAGAARORCCYP2C9
SCHEMBL7183830 0.84 KMT2A (0.36) ALDH1A1LMNAGAARORCCYP2C9
SCHEMBL7184882 0.84 LMNA (0.35) ALDH1A1LMNAGAAMAPK13MAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 ALDH1A1 3416/4885LMNA 3241/4885GAA 4753/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 ALDH1A1 3984/4885LMNA 3247/4885GAA 4793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.