Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7180179 | 1.00 | MAOB (0.37) | MAOBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL4454227 | 0.96 | MAOB (0.34) | MAOB | |
| SCHEMBL7627021 | 0.96 | MAOB (0.34) | MAOB | |
| SCHEMBL7669289 | 0.94 | MMP1 (0.33) | MAOBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7641341 | 0.90 | MAOB (0.32) | MAOBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7633849 | 0.89 | MAOB (0.31) | MAOBHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL3404398 | 0.89 | PDCD1 (0.35) | ALDH1A1MAPK1 | |
| SCHEMBL31253552 | 0.89 | PDCD1 (0.35) | ALDH1A1MAPK1 | |
| SCHEMBL7629353 | 0.88 | — | — | |
| SCHEMBL7629051 | 0.88 | NPC1 (0.31) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066110-B1 | ION EXCHANGED ALUMINIUM-MAGNESIUM SILICATE OR FLUORINATED MAGNESIUM SILICATE AEROGELS AND CATALYST SUPPORTS THEREFROM | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-05-21 | — | — | EP | disclosed |