SCHEMBL3404398

SCHEMBL3404398

CC1=Cc2c(-c3ccccc3)cccc2C1[Zr]C1C(C)=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDCD1 Q15116 1/20 0.35
CD274 Q9NZQ7 1/20 0.35
USP30 Q70CQ3 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
BRD4 O60885 1/20 0.32
HNF4A P41235 1/20 0.32
CYP2A6 P11509 2/20 0.31
CYP2B6 P20813 1/20 0.31
ALDH1A1 P00352 4/20 0.31
HSD17B10 Q99714 2/20 0.31
HPGD P15428 2/20 0.31
BCL2L1 Q07817 1/20 0.31
MAPK1 P28482 1/20 0.31
NPC1 O15118 1/20 0.30
TSHR P16473 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
HTR1A P08908 1/20 0.30
HTR7 P34969 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31253552 1.00 PDCD1 (0.35) PDCD1CD274USP30CHRNB2CHRNA4
Hydrochloric Acid SCHEMBL7943365 0.97 PDCD1 (0.33) PDCD1CD274USP30CHRNB2CHRNA4
SCHEMBL5678404 0.95 PDCD1 (0.33) PDCD1CD274USP30CHRNB2CHRNA4
SCHEMBL14905713 0.93 NPC1 (0.33) PDCD1CD274USP30CHRNB2CHRNA4
SCHEMBL7983533 0.93 PDCD1 (0.34) PDCD1CD274USP30CHRNB2CHRNA4
SCHEMBL6531333 0.90 PDCD1 (0.33) PDCD1CD274HTR7
SCHEMBL4465450 0.89 KDM4E (0.34) PDCD1CD274CHRNB2CHRNA4CYP2A6
SCHEMBL4469094 0.89 ALDH1A1 (0.37) PDCD1CD274ALDH1A1HSD17B10HPGD
SCHEMBL7180179 0.89 MAOB (0.37) ALDH1A1MAPK1
SCHEMBL7180174 0.89 MAOB (0.37) ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1238026-B2 PIGMENT CONCENTRATES AND METHODS FOR PRODUCTION THEREOF BASF AG (DE) 2007-01-24 EP claimed
EP-1040140-B1 VINYL-CONTAINING STEREOSPECIFIC POLYPROPYLENE MACROMERS EXXONMOBIL CHEM PATENTS INC (US) 2004-07-28 EP claimed
EP-1040134-A1 MIXED CATALYST SYSTEM UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-10-04 EP claimed
WO-1999031147-A1 MIXED CATALYST SYSTEM UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 1999-06-24 WO claimed
CN-112912357-B Process and apparatus for producing polyalphaolefin trimer 埃克森美孚化学专利公司 2024-06-04 CN disclosed
CN-113015755-B Metallocene dimer selective catalyst and process for preparing poly alpha-olefin dimer 埃克森美孚化学专利公司 2023-09-08 CN disclosed
CN-113039221-B Process for preparing poly alpha-olefin trimer 埃克森美孚化学专利公司 2023-07-18 CN disclosed
CN-109952324-B Blocked multi-or double-headed compositions suitable for chain shuttling and methods of making the same 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
US-8835587-B2 Catalyst system, process for olefin polymerization, and polymer compositions produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-09-16 US disclosed
US-20140038486-A1 Catalyst System, Process For Olefin Polymerization, And Polymer Compositions Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2014-02-06 US disclosed
EP-2222723-B1 METHOD FOR CONTROLLING BIMODAL CATALYST ACTIVITY DURING POLYMERIZATION UNIVATION TECH LLC (US) 2013-02-27 EP disclosed
US-8318872-B2 Method for controlling bimodal catalyst activity during polymerization UNIVATION TECHNOLOGIES, LLC (US) 2012-11-27 US disclosed
US-20020107342-A1 Combines a catalyst component containing slurry and a catalyst component containing solution to form the completed catalyst composition for introduction into the polymerization reactor; polymerizing olefins UNIVATION TECHNOLOGIES, LLC 2002-08-08 US disclosed
WO-2002046243-A2 POLYMERIZATION PROCESS UNIVATION TECHNOLOGIES, LLC (US) 2002-06-13 WO disclosed
WO-2002046250-A2 CATALYST COMPOSITION, METHOD OF POLYMERIZATION AND POLYMER THEREFROM UNIVATION TECHNOLOGIES, LLC (US) 2002-06-13 WO disclosed
WO-2001004167-A1 COORDINATION POLYMERIZATION CATALYSTS COMPRISING AN ION EXCHANGE RESIN THE DOW CHEMICAL COMPANY (US) 2001-01-18 WO disclosed
EP-1066110-A1 ION EXCHANGED ALUMINIUM-MAGNESIUM SILICATE OR FLUORINATED MAGNESIUM SILICATE AEROGELS AND CATALYST SUPPORTS THEREFROM THE DOW CHEMICAL COMPANY (US) 2001-01-10 EP disclosed
US-6069213-A Mixed catalyst system UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) 2000-05-30 US disclosed
WO-1999048605-A1 ION EXCHANGED ALUMINIUM-MAGNESIUM OR FLUORINATED MAGNESIUM SILICATE AEROGELS AND CATALYST SUPPORTS THEREFROM THE DOW CHEMICAL COMPANY (US) 1999-09-30 WO disclosed
CN-1200734-A Supportable biscyclopentadienyl metal complexes DOW CHEMICAL CO (US) 1998-12-02 CN disclosed