Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1046749 | 0.98 | HSD17B10 (0.59) | HSD17B10BRD4LIMK2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7176914 | 0.97 | HSD17B10 (0.57) | HSD17B10BRD4LIMK2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7175511 | 0.97 | HSD17B10 (0.57) | HSD17B10BRD4LIMK2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7176860 | 0.97 | HSD17B10 (0.57) | HSD17B10BRD4LIMK2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7172278 | 0.97 | HSD17B10 (0.57) | HSD17B10BRD4LIMK2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7177551 | 0.97 | HSD17B10 (0.57) | HSD17B10BRD4LIMK2ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL7171378 | 0.97 | HSD17B10 (0.57) | HSD17B10BRD4LIMK2ALDH1A1MEN1 | |
| SCHEMBL2839207 | 0.85 | HSD17B10 (0.59) | HSD17B10BRD4LIMK2ALDH1A1MEN1 | |
| SCHEMBL17621 | 0.81 | HSD17B10 (0.62) | HSD17B10BRD4LIMK2ALDH1A1MEN1 | |
| Fluoride SCHEMBL10339918 | 0.79 | HSD17B10 (0.60) | HSD17B10BRD4LIMK2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |