SCHEMBL7180346

SCHEMBL7180346

Cc1cccc(OC(=O)C(=O)Oc2ccccc2)c1

nearest known ligand 0.67

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.67
KMT2A Q03164 3/20 0.55
ALDH1A1 P00352 2/20 0.55
MEN1 O00255 2/20 0.55
PPARG P37231 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
GAA P10253 1/20 0.51
BCHE P06276 1/20 0.51
MAPT P10636 2/20 0.50
ACHE P22303 1/20 0.50
ALOX5 P09917 1/20 0.49
POLB P06746 1/20 0.49
MAPK1 P28482 3/20 0.47
FAAH O00519 1/20 0.47
CYP3A4 P08684 1/20 0.47
HTT P42858 1/20 0.46
ALOX15 P16050 1/20 0.46
HSD17B10 Q99714 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7922562 0.94 LMNA (0.74) LMNAKMT2AALDH1A1MEN1PPARG
SCHEMBL7176954 0.89 LMNA (0.67) LMNAKMT2AALDH1A1MEN1PPARG
SCHEMBL7179623 0.89 LMNA (0.67) LMNAKMT2AALDH1A1MEN1PPARG
SCHEMBL11556061 0.85 LMNA (0.72) LMNAKMT2AALDH1A1MEN1PPARG
SCHEMBL121195 0.84 LMNA (0.78) LMNAKMT2AALDH1A1MEN1PPARG
SCHEMBL29398813 0.84 LMNA (0.78) LMNAKMT2AALDH1A1MEN1PPARG
SCHEMBL15842740 0.84 LMNA (0.61) LMNAKMT2AALDH1A1MEN1PPARG
SCHEMBL15842739 0.84 LMNA (0.61) LMNAKMT2AALDH1A1MEN1PPARG
SCHEMBL21551659 0.83 LMNA (0.65) LMNAKMT2AALDH1A1MEN1PPARG
SCHEMBL819332 0.82 LMNA (0.74) LMNAKMT2AALDH1A1MEN1PPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3189029-B1 METHOD OF MELT POLYMERIZING POLYCARBONATE AND THE POLYCARBONATE MADE THEREFROM SABIC GLOBAL TECHNOLOGIES BV (NL) 2019-02-20 EP disclosed
EP-2970096-B1 PROCESS FOR PURIFICATION OF DIPHENYL CARBONATE FOR THE MANUFACTURING OF HIGH QUALITY POLYCARBONATE SABIC GLOBAL TECHNOLOGIES BV (NL) 2018-08-08 EP disclosed
EP-2816068-B1 Process for the manufacture of polycarbonate compositions SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-12-27 EP disclosed
US-20170306090-A1 METHOD FOR MAKING POLYCARBONATE USING A LIQUID KETONE MIXTURE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-10-26 US disclosed
EP-3215551-A1 METHOD FOR MAKING POLYCARBONATE USING A LIQUID KETONE MIXTURE SABIC Global Technologies B.V. (NL) 2017-09-13 EP disclosed
US-9738590-B1 Method of melt polymerizing polycarbonate and the polycarbonate made therefrom SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-22 US disclosed
US-20170233328-A1 METHOD OF MELT POLYMERIZING POLYCARBONATE AND THE POLYCARBONATE MADE THEREFROM SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-17 US disclosed
US-9732028-B2 Process for purification of diphenyl carbonate for the manufacturing of high quality polycarbonate SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-08-15 US disclosed
EP-2778186-B1 Production of a polycarbonate with limited metal residuals SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-07-12 EP disclosed
EP-3189029-A2 METHOD OF MELT POLYMERIZING POLYCARBONATE AND THE POLYCARBONATE MADE THEREFROM SABIC Global Technologies B.V. (NL) 2017-07-12 EP disclosed
US-20140378643-A1 PROCESS FOR THE MANUFACTURE OF POLYCARBONATE COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2014-12-25 US disclosed
EP-2816068-A1 Process for the manufacture of polycarbonate compositions SABIC Innovative Plastics IP B.V. (NL) 2014-12-24 EP disclosed
WO-2014141108-A1 PRODUCTION OF A POLYCARBONATE WITH LIMITED METAL RESIDUALS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-09-18 WO disclosed
WO-2014141107-A2 PROCESS FOR PURIFICATION OF DIPHENYL CARBONATE FOR THE MANUFACTURING OF HIGH QUALITY POLYCARBONATE SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2014-09-18 WO disclosed
US-20140275473-A1 PROCESS FOR PURIFICATION OF DIPHENYL CARBONATE FOR THE MANUFACTURING OF HIGH QUALITY POLYCARBONATE SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2014-09-18 US disclosed
US-20140275466-A1 PRODUCTION OF A POLYCARBONATE WITH LIMITED METAL RESIDUALS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2014-09-18 US disclosed
EP-2778186-A1 Production of a polycarbonate with limited metal residuals SABIC Innovative Plastics IP B.V. (NL) 2014-09-17 EP disclosed
EP-0987285-B1 PROCESS FOR THE PREPARATION OF AROMATIC POLYCARBONATE TEIJIN LTD (JP) 2003-07-09 EP disclosed
US-6265524-B1 PRODUCING AROMATIC POLYCARBONATE THROUGH ESTER INTERCHANGE REACTION BETWEEN AROMATIC DIHYDROXY COMPOUND AND AROMATIC CARBONIC ACID DIESTER OBTAINED THROUGH DECARBONYLATION REACTION OF AROMATIC OXALIC ACID DIESTER TEIJIN LIMITED (JP) 2001-07-24 US disclosed
EP-0987285-A1 PROCESS FOR THE PREPARATION OF AROMATIC POLYCARBONATE TEIJIN LIMITED (JP) 2000-03-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170233328-A1 METHOD OF MELT POLYMERIZING POLYCARBONATE AND THE POLYCARBONATE MADE THEREFROM PHF2, CYP21A2, HSD11B2 LMNA 2360/4885KMT2A 477/4885ALDH1A1 1061/4885
US-20140275473-A1 PROCESS FOR PURIFICATION OF DIPHENYL CARBONATE FOR THE MANUFACTURING OF HIGH QUALITY POLYCARBONATE DKC1, PKD1, UBLCP1 LMNA 2406/4885KMT2A 671/4885ALDH1A1 3916/4885
US-20140275466-A1 PRODUCTION OF A POLYCARBONATE WITH LIMITED METAL RESIDUALS BMI1, EZH2, SUV39H2 LMNA 4677/4885KMT2A 186/4885ALDH1A1 4642/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.