SCHEMBL819332

SCHEMBL819332

Cc1cccc(OC(=O)Oc2cccc(C)c2)c1

nearest known ligand 0.74

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.74
ACHE P22303 1/20 0.56
MAPT P10636 2/20 0.54
ALOX5 P09917 1/20 0.53
POLB P06746 1/20 0.53
MAPK1 P28482 2/20 0.53
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53
ALDH1A1 P00352 2/20 0.51
FAAH O00519 1/20 0.51
CYP3A4 P08684 1/20 0.51
GAA P10253 1/20 0.51
KMT2A Q03164 3/20 0.51
MEN1 O00255 2/20 0.51
BCHE P06276 1/20 0.51
PPARG P37231 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29418226 1.00 LMNA (0.74) LMNAACHEMAPTALOX5POLB
SCHEMBL16675180 0.96 LMNA (0.69) LMNAACHEMAPTALOX5POLB
SCHEMBL7176954 0.94 LMNA (0.67) LMNAACHEMAPTALOX5POLB
SCHEMBL10533332 0.92 LMNA (0.65) LMNAACHEMAPTALOX5POLB
SCHEMBL410350 0.90 LMNA (0.67) LMNAACHEMAPTALOX5POLB
SCHEMBL7922562 0.87 LMNA (0.74) LMNAACHEMAPTALOX5POLB
SCHEMBL308933 0.87 LMNA (0.62) LMNAACHEMAPTALOX5POLB
SCHEMBL1034093 0.86 LMNA (0.57) LMNAACHEMAPTALOX5POLB
SCHEMBL6890525 0.85 LMNA (0.61) LMNAACHEMAPTALOX5POLB
SCHEMBL2738445 0.85 LMNA (0.61) LMNAACHEMAPTALOX5POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022077450-A1 POLYCARBONATE, PREPARATION METHOD THEREFOR AND USE THEREOF 万华化学集团股份有限公司 2022-04-21 WO claimed
CN-112175178-A Polycarbonate and preparation method and application thereof 万华化学集团股份有限公司 2021-01-05 CN claimed
US-6346597-B1 REACTION OF DIACID WITH CARBONIC ACID DIESTER AND CATALYST GENERAL ELECTRIC COMPANY 2002-02-12 US claimed
WO-2001048050-A1 METHOD FOR MAKING POLYESTER CARBONATES GENERAL ELECTRIC COMPANY (US) 2001-07-05 WO claimed
US-20260139096-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER TEIJIN LIMITED (JP) 2026-05-21 US disclosed
US-12540218-B2 Polycarbonate/polyorganosiloxane copolymer and resin composition including said copolymer IDEMITSU KOSAN CO., LTD. (JP) 2026-02-03 US disclosed
US-20250368777-A1 POLYCARBONATE-POLYORGANOSILOXANE COPOLYMER IDEMITSU KOSAN CO.,LTD. (JP) 2025-12-04 US disclosed
US-12398237-B2 Polycarbonate/polyorganosiloxane copolymer and resin composition including said copolymer IDEMITSU KOSAN CO., LTD. (JP) 2025-08-26 US disclosed
US-12384881-B2 Polycarbonate/polyorganosiloxane copolymer and resin composition including said copolymer IDEMITSU KOSAN CO., LTD. (JP) 2025-08-12 US disclosed
CN-120082186-A Resin composition 帝人株式会社 2025-06-03 CN disclosed
CN-114752053-B Polycarbonate resin, method for producing same, and optical lens 三菱瓦斯化学株式会社 2025-05-30 CN disclosed
CN-115960345-B Polycarbonate resin, method for producing same, and optical lens 三菱瓦斯化学株式会社 2025-05-06 CN disclosed
US-4980420-A Benzotriazole and oxanilide UV absorber hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1990-12-25 US disclosed
US-4853361-A FLUORAN-TYPE LEUCO DYES JUJO PAPER CO., LTD. (JP) 1989-08-01 US disclosed
EP-0149558-B1 HIGH EFFICIENCY POLYMERIZATION CATALYST COMPONENT FOR USE IN THE POLYMERIZATION OF PROPYLENE AND HIGHER ALPHA-OLEFINS EXXON RESEARCH AND ENGINEERING COMPANY (US) 1989-03-15 EP disclosed
US-4677088-A COORDINATION CATALYST ORGANOALUMINUM COMPOUND AND LEWIS BASE EXXON CHEMICAL PATENTS INC. (US) 1987-06-30 US disclosed
EP-0156103-A1 Process for the polymerization of polyester-carbonates GENERAL ELECTRIC COMPANY (US) 1985-10-02 EP disclosed
EP-0149558-A2 High efficiency polymerization catalyst component for use in the polymerization of propylene and higher alpha-olefins EXXON RESEARCH AND ENGINEERING COMPANY (US) 1985-07-24 EP disclosed
US-4525467-A MIXED ALUMINUM HYDROCARBYL-LEWIS BASE COORDINATION CATALYST EXXON RESEARCH & ENGINEERING CO. (US) 1985-06-25 US disclosed
US-4331558-A OLEFINS, MAGNESIUM OR MANGANESE HALIDE, ARYL CARBONATE, TITANIUM TETRAHALIDE, ORGANOALUMINUM COMPOUND PHILLIPS PETROLEUM COMPANY (US) 1982-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12540218-B2 Polycarbonate/polyorganosiloxane copolymer and resin composition including said copolymer COL1A1, MACF1, HAO2 LMNA 2894/4885ACHE 4858/4885MAPT 3749/4885
US-20260139096-A1 THERMOPLASTIC RESIN AND OPTICAL MEMBER HEATR1, HSF1, WHR1 LMNA 591/4885ACHE 4835/4885MAPT 2126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.