Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7185035 | 0.96 | KDM4E (0.31) | KDM4EALDH1A1LMNAGAAMAPT | |
| Hydrochloric Acid SCHEMBL7178354 | 0.96 | KDM4E (0.31) | KDM4EALDH1A1LMNAGAAMAPT | |
| Hydrochloric Acid SCHEMBL7182017 | 0.96 | KDM4E (0.31) | KDM4EALDH1A1LMNAGAAMAPT | |
| Hydrochloric Acid SCHEMBL7176713 | 0.96 | KDM4E (0.31) | KDM4EALDH1A1LMNAGAAMAPT | |
| Hydrochloric Acid SCHEMBL7173214 | 0.96 | KDM4E (0.31) | KDM4EALDH1A1LMNAGAAMAPT | |
| Hydrochloric Acid SCHEMBL7176570 | 0.96 | KDM4E (0.31) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL6912296 | 0.96 | KDM4E (0.33) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL6912292 | 0.96 | KDM4E (0.33) | KDM4EALDH1A1LMNAGAAMAPT | |
| Hydrochloric Acid SCHEMBL7184006 | 0.90 | RAPGEF4 (0.32) | — | |
| Hydrochloric Acid SCHEMBL7176564 | 0.88 | MEN1 (0.37) | KDM4EALDH1A1MAPTPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |