SCHEMBL7180671

SCHEMBL7180671

CCOCCOc1ccc(PC(=O)c2c(C)cccc2C)c(C)c1.[LiH]

nearest known ligand 0.43

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 10/20 0.43
APP P05067 1/20 0.41
LMNA P02545 2/20 0.40
MAPT P10636 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
TAAR1 Q96RJ0 1/20 0.40
KDM4E B2RXH2 2/20 0.39
MAPK1 P28482 1/20 0.38
ALDH1A1 P00352 2/20 0.38
THRA P10827 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7180489 0.92 FFAR1 (0.44) FFAR1APPLMNAMAPTL3MBTL1
SCHEMBL7180243 0.91 FFAR1 (0.46) FFAR1LMNAMAPTL3MBTL1TDP1
SCHEMBL7180645 0.91 LMNA (0.44) FFAR1APPLMNAMAPTL3MBTL1
SCHEMBL7181700 0.91 FFAR1 (0.39) FFAR1APPLMNAMAPTL3MBTL1
SCHEMBL7188475 0.89 THRB (0.41) KMT2ATHRA
SCHEMBL7186699 0.89 KMT2A (0.45) FFAR1LMNAMAPTL3MBTL1TDP1
SCHEMBL7177209 0.89 SMN1; SMN2 (0.41) LMNAMAPTL3MBTL1KMT2AKDM4E
SCHEMBL7174730 0.89 LMNA (0.42) FFAR1APPLMNAMAPTL3MBTL1
SCHEMBL7188420 0.88 TDP1 (0.39) FFAR1LMNAL3MBTL1TDP1KDM4E
SCHEMBL7175775 0.87 KDM4E (0.38) FFAR1LMNAMAPTTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 FFAR1 671/4885APP 4723/4885LMNA 3241/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 FFAR1 711/4885APP 4740/4885LMNA 3247/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.