Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | HPGD | P15428 | 7/20 | 0.57 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7172465 | 0.97 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTHTT | |
| Hydrochloric Acid SCHEMBL7176679 | 0.97 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTHTT | |
| Hydrochloric Acid SCHEMBL7178412 | 0.97 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTHTT | |
| Hydrochloric Acid SCHEMBL7178576 | 0.97 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTHTT | |
| Hydrochloric Acid SCHEMBL7176647 | 0.97 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTHTT | |
| Hydrochloric Acid SCHEMBL7171322 | 0.97 | ALDH1A1 (0.57) | ALDH1A1KDM4EHPGDMAPTHTT | |
| Hydrochloric Acid SCHEMBL7173379 | 0.88 | MAPT (0.59) | ALDH1A1KDM4EHPGDMAPTHTT | |
| SCHEMBL13351524 | 0.86 | ALDH1A1 (0.66) | ALDH1A1KDM4EHPGDMAPTHTT | |
| Hydrochloric Acid SCHEMBL7177348 | 0.85 | TP53 (0.60) | ALDH1A1KDM4EHPGDMAPTHTT | |
| Hydrochloric Acid SCHEMBL7175705 | 0.84 | MAPT (0.59) | ALDH1A1KDM4EHPGDMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |