⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13293233 | 0.71 | — | — | |
| SCHEMBL13429391 | 0.69 | MGAM (0.30) | — | |
| Shikimic Acid SCHEMBL5875125 | 0.61 | — | — | |
| SCHEMBL13811311 | 0.60 | ALDH1A1 (0.32) | — | |
| SCHEMBL10168016 | 0.60 | ALDH1A1 (0.32) | — | |
| SCHEMBL10558611 | 0.60 | — | — | |
| SCHEMBL13912374 | 0.60 | — | — | |
| SCHEMBL13764744 | 0.60 | — | — | |
| SCHEMBL14905976 | 0.59 | CHRM3 (0.36) | — | |
| SCHEMBL1716907 | 0.59 | CHRM3 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586402-B1 | LH-RH peptide analogues, their uses and pharmaceutical compositions containing them | LABORATOIRE THERAMEX (MC) | 2003-07-01 | — | — | US | disclosed |
| EP-1117420-B1 | PHARMACEUTICAL COMPOSITIONS BASED ON ALPHA-CYCLODEXTRIN FOR THE ORAL ADMINISTRATION OF LH-RH ANALOGUES | THERAMEX (MC) | 2002-06-05 | — | — | EP | disclosed |
| EP-0984982-B1 | LH-RH PEPTIDE ANALOGUES, THEIR USES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | THERAMEX (MC) | 2001-08-16 | — | — | EP | disclosed |
| EP-1117420-A1 | PHARMACEUTICAL COMPOSITIONS BASED ON ALPHA-CYCLODEXTRIN FOR THE ORAL ADMINISTRATION OF LH-RH ANALOGUES | LABORATOIRE THERAMEX S.A. (MC) | 2001-07-25 | — | — | EP | disclosed |
| EP-0998940-A1 | Pharmaceutical compositions based on alpha-cyclodextrin for the oral administration of LH-RH analogues | LABORATOIRE THERAMEX (MC) | 2000-05-10 | — | — | EP | disclosed |
| WO-2000018423-A1 | PHARMACEUTICAL COMPOSITIONS BASED ON ALPHA-CYCLODEXTRIN FOR THE ORAL ADMINISTRATION OF LH-RH ANALOGUES | LABORATOIRE THERAMEX (MC) | 2000-04-06 | — | — | WO | disclosed |
| EP-0984982-A1 | LH-RH PEPTIDE ANALOGUES, THEIR USES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 2000-03-15 | — | — | EP | disclosed |
| WO-1998055505-A1 | LH-RH PEPTIDE ANALOGUES, THEIR USES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LABORATOIRE THERAMEX (MC) | 1998-12-10 | — | — | WO | disclosed |
| EP-0882736-A1 | LH-RH peptide analogues, their uses and pharmaceutical compositions containing them | LABORATOIRE THERAMEX S.A. (MC) | 1998-12-09 | — | — | EP | disclosed |