SCHEMBL7181097

SCHEMBL7181097

Cc1cc(C)c(C(=O)P(=O)(C(=O)c2c(Cl)cccc2Cl)c2ccccc2)c(C)c1

nearest known ligand 0.42

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
GAA P10253 3/20 0.38
MAPT P10636 2/20 0.38
RAB9A P51151 3/20 0.37
TP53 P04637 1/20 0.37
PTK2B Q14289 1/20 0.36
SMO Q99835 1/20 0.36
TYK2 P29597 1/20 0.36
ALDH1A1 P00352 1/20 0.36
POLB P06746 1/20 0.36
KCNK3 O14649 1/20 0.36
KCNK9 Q9NPC2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182411 0.94 KMT2A (0.40) KMT2AMEN1GAAMAPTRAB9A
SCHEMBL7188746 0.90 MEN1 (0.39) KMT2AMEN1GAAMAPTRAB9A
SCHEMBL7174811 0.90 TYK2 (0.44) KMT2AGAAMAPTPTK2BTYK2
SCHEMBL15158 0.89 LMNA (0.40) KMT2AMEN1MAPTRAB9AALDH1A1
SCHEMBL7184527 0.89 MEN1 (0.38) KMT2AMEN1MAPTRAB9ATP53
SCHEMBL7182407 0.89 CA12 (0.40) KMT2AMEN1GAAMAPTRAB9A
SCHEMBL7180487 0.88 LMNA (0.37) KMT2AMEN1MAPTRAB9AALDH1A1
SCHEMBL25250816 0.88 LMNA (0.39) KMT2AMEN1MAPTRAB9AALDH1A1
SCHEMBL30988127 0.88 KMT2A (0.41) KMT2AMEN1MAPTRAB9AALDH1A1
Lithium SCHEMBL30307090 0.88 LMNA (0.39) KMT2AMEN1MAPTRAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 KMT2A 1586/4885MEN1 2312/4885GAA 4753/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 KMT2A 956/4885MEN1 2263/4885GAA 4793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.