SCHEMBL7188746

SCHEMBL7188746

Cc1cc(C)c(C(=O)P(=O)(C(=O)c2c(Cl)cc(Cl)cc2Cl)c2ccccc2)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.39
KMT2A Q03164 4/20 0.39
RAB9A P51151 3/20 0.36
MAPT P10636 2/20 0.36
LMNA P02545 2/20 0.36
HTT P42858 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
PTPRC P08575 1/20 0.36
TP53 P04637 2/20 0.35
GPR27 Q9NS67 1/20 0.35
STK39 Q9UEW8 1/20 0.35
NPC1 O15118 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7181097 0.90 KMT2A (0.42) MEN1KMT2ARAB9AMAPTTP53
SCHEMBL7174651 0.90 FABP3 (0.39) MAPTLMNAHTTNPSR1PTPRC
SCHEMBL15158 0.88 LMNA (0.40) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL7189279 0.88 FLT1 (0.35) RAB9AMAPTLMNAHTTNPSR1
SCHEMBL25250816 0.87 LMNA (0.39) MEN1KMT2ARAB9AMAPTLMNA
Lithium SCHEMBL30307090 0.87 LMNA (0.39) MEN1KMT2ARAB9AMAPTLMNA
Iodide SCHEMBL29831346 0.87 LMNA (0.39) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL28310329 0.87 LMNA (0.39) MEN1KMT2ARAB9AMAPTLMNA
SCHEMBL30988127 0.87 KMT2A (0.41) MEN1KMT2ARAB9AMAPTLMNA
Ammonia Solution, Strong SCHEMBL28286046 0.87 LMNA (0.40) MEN1KMT2ARAB9AMAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 MEN1 2312/4885KMT2A 1586/4885RAB9A 1818/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 MEN1 2263/4885KMT2A 956/4885RAB9A 2155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.