Sugi Predict

Sugi Predict / Compounds / SCHEMBL7181264

SCHEMBL7181264

SCHEMBL7181264

Cc1cc(C)c(C(=O)P(=O)(C(=O)c2c(C)cccc2-c2ccccc2)c2ccccc2)c(C)c1C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.35
▸ FOLH1 Q04609 1/20 0.35
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ NR1H4 Q96RI1 2/20 0.34
▸ FFAR1 O14842 2/20 0.34
▸ ALDH1A1 P00352 3/20 0.34
▸ MEN1 O00255 1/20 0.34
▸ CYP1A2 P05177 1/20 0.34
▸ CYP3A4 P08684 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ CYP2D6 P10635 1/20 0.34
▸ CYP2C9 P11712 1/20 0.34
▸ CYP2C19 P33261 1/20 0.34
▸ HTT P42858 1/20 0.34
▸ KMT2A Q03164 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34
▸ PDCD1 Q15116 1/20 0.33
▸ CD274 Q9NZQ7 1/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ NPC1 O15118 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7177289 0.90 L3MBTL1 (0.34) LMNAL3MBTL1ALDH1A1MEN1CYP1A2
SCHEMBL7180584 0.88 FOLH1 (0.40) LMNAFOLH1L3MBTL1NR1H4FFAR1
SCHEMBL7190153 0.87 L3MBTL1 (0.39) LMNAFOLH1L3MBTL1NR1H4FFAR1
SCHEMBL7181616 0.87 KMT2A (0.36) LMNAALDH1A1MEN1CYP1A2GAA
SCHEMBL7181615 0.84 KMT2A (0.33) ALDH1A1MEN1CYP1A2GAAKMT2A
SCHEMBL7184793 0.84 RXRB (0.37) LMNAFOLH1L3MBTL1NR1H4FFAR1
SCHEMBL7174855 0.84 GFER (0.35) LMNAALDH1A1MEN1CYP1A2GAA
SCHEMBL7180464 0.84 KMT2A (0.34) LMNAALDH1A1MEN1CYP1A2GAA
SCHEMBL7181152 0.84 TYK2 (0.39) GAACYP2C9KMT2AMAPTRAB9A
SCHEMBL7175134 0.82 FABP3 (0.42) LMNAFOLH1MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 LMNA 3241/4885FOLH1 4775/4885L3MBTL1 302/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 LMNA 3247/4885FOLH1 4772/4885L3MBTL1 126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.