Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | ARG2 | P78540 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5831023 | 0.77 | MAOB (0.50) | MAOBCA1CA2ARG2KCNH2 | |
| SCHEMBL7980743 | 0.76 | MAOB (0.61) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL6662115 | 0.76 | ALDH1A1 (0.38) | MAOBKCNH2TSHRALDH1A1 | |
| SCHEMBL7980741 | 0.76 | MAOB (0.61) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL1524697 | 0.75 | MAOB (1.00) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL155054 | 0.75 | MAOB (1.00) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL155055 | 0.75 | MAOB (1.00) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL10706531 | 0.75 | ALDH1A1 (0.39) | CA1CA2HSP90AA1ALDH1A1 | |
| SCHEMBL6668054 | 0.72 | MAOB (0.56) | MAOBCA1CA2ARG2TOP1 | |
| SCHEMBL9983229 | 0.71 | MAOB (0.54) | MAOBCA1CA2ARG2TOP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771809-B1 | Method of manufacturing a polysiloxane charge transporting material | DOW CORNING ASIA LTD (JP) | 2003-04-02 | — | — | EP | disclosed |
| EP-0771806-B1 | Silicon containing charge transport compounds | DOW CORNING ASIA LTD (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-5840816-A | Method of manufacturing a polysiloxane charge transporting material | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0771806-A1 | Silicon containing charge transport compounds | DOW CORNING ASIA, Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |
| EP-0771809-A1 | Method of manufacturing a polysiloxane charge transporting material | DOW CORNING ASIA, Ltd. (JP) | 1997-05-07 | — | — | EP | disclosed |