Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18054856 | 0.78 | TSHR (0.39) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL10706531 | 0.77 | ALDH1A1 (0.39) | ALDH1A1GLAMEN1KMT2AL3MBTL1 | |
| SCHEMBL4468762 | 0.77 | SOAT2 (0.44) | ALDH1A1TSHRKDM4ECYP3A4TDP1 | |
| SCHEMBL4468496 | 0.77 | SOAT2 (0.44) | ALDH1A1TSHRKDM4ECYP3A4TDP1 | |
| SCHEMBL4474820 | 0.77 | SOAT2 (0.44) | ALDH1A1TSHRKDM4ECYP3A4TDP1 | |
| SCHEMBL4468500 | 0.77 | SOAT2 (0.44) | ALDH1A1TSHRKDM4ECYP3A4TDP1 | |
| SCHEMBL4468757 | 0.77 | SOAT2 (0.44) | ALDH1A1TSHRKDM4ECYP3A4TDP1 | |
| SCHEMBL3684137 | 0.76 | ALDH1A1 (0.40) | ALDH1A1TSHRGLAMEN1KMT2A | |
| SCHEMBL7181286 | 0.76 | MAOB (0.58) | ALDH1A1TSHRKCNH2MAOB | |
| SCHEMBL15360345 | 0.74 | TSHR (0.32) | ALDH1A1TSHRGLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0877028-B1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEM IND CO (JP) | 2004-08-25 | — | — | EP | disclosed |
| US-6084123-A | REACTING AN IMINE WITH A PHOSPHONIC ACID ESTER USING AN ASYMMETRIC CATALYST OF A RARE EARTH METAL/ALKALI METAL-BINAPHTHOL COMPLEX; HYDROGENATION AND ACIDOLYSIS | HOKKO CHEMICAL INDUSTRY CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0877028-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE 1-AMINOPHOSPHONIC ACID DERIVATIVES AND NOVEL PHOSPHONATE COMPOUNDS | HOKKO CHEMICAL INDUSTRY CO. LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |