Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 11/20 | 0.73 |
| ▸ | MAPT | P10636 | 2/20 | 0.67 |
| ▸ | LMNA | P02545 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | PKM | P14618 | 1/20 | 0.64 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | KDR | P35968 | 1/20 | 0.56 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.56 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18995909 | 0.88 | STAT3 (0.64) | PGRMAPTLMNAPKMSTAT3 | |
| SCHEMBL7178676 | 0.86 | PGR (0.71) | PGRMAPTLMNATDP1PKM | |
| SCHEMBL28400969 | 0.85 | PGR (0.76) | PGRMAPTLMNATDP1PKM | |
| SCHEMBL3756876 | 0.85 | PGR (1.00) | PGRMAPTLMNATDP1PKM | |
| SCHEMBL6275068 | 0.85 | CYP3A4 (0.62) | PGRSTAT3 | |
| SCHEMBL28121847 | 0.84 | PGR (0.73) | PGRMAPTLMNATDP1PKM | |
| SCHEMBL97999 | 0.84 | PGR (0.73) | PGRMAPTLMNATDP1PKM | |
| SCHEMBL21086842 | 0.83 | MAPT (0.60) | PGRMAPTLMNAPKMSTAT3 | |
| SCHEMBL5329565 | 0.83 | PGR (0.80) | PGRMAPTLMNATDP1PKM | |
| SCHEMBL5046668 | 0.81 | PGR (0.73) | PGRMAPTLMNATDP1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579829-B2 | Aromatic sulfonamide compound | MITSUI CHEMICALS, INC. (JP) | 2003-06-17 | — | — | US | disclosed |
| EP-1138517-A2 | Developer composition and heat sensitive recording material | Mitsui Chemicals, Inc. (JP) | 2001-10-04 | — | — | EP | disclosed |