Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR5A1 | Q13285 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.48 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.47 |
| ▸ | RARB | P10826 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181365 | 0.99 | NR5A1 (0.48) | NR5A1TP53TSHRPLA2G4BS1PR1 | |
| SCHEMBL7180725 | 0.96 | FAAH (0.44) | NR5A1TP53TSHRS1PR1S1PR5 | |
| SCHEMBL7184936 | 0.94 | NR5A1 (0.45) | NR5A1TP53TSHRPLA2G4BS1PR1 | |
| SCHEMBL7189280 | 0.93 | MAPT (0.45) | NR5A1TP53TSHRPLA2G4BS1PR1 | |
| SCHEMBL7183725 | 0.93 | NR5A1 (0.43) | NR5A1TP53TSHRPLA2G4BS1PR1 | |
| SCHEMBL7182674 | 0.92 | MAPT (0.46) | NR5A1TP53TSHRPLA2G4BS1PR1 | |
| SCHEMBL7187454 | 0.91 | L3MBTL1 (0.44) | TP53 | |
| SCHEMBL7183228 | 0.90 | FAAH (0.41) | NR5A1TP53TSHRS1PR1S1PR5 | |
| SCHEMBL7181016 | 0.89 | L3MBTL1 (0.45) | — | |
| SCHEMBL7182620 | 0.87 | NR5A1 (0.50) | NR5A1TP53TSHRPLA2G4BRARB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6579663-B2 | Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-06-17 | — | — | US | disclosed |
| US-20020107413-A1 | Organometallic monoacylarylphosphines | WOLF JEAN-PIERRE (CH) | 2002-08-08 | — | — | US | disclosed |
| US-6399805-B2 | SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-06-04 | — | — | US | disclosed |
| US-20010031898-A1 | Organometallic monoacylarylphosphines | CIBA SPECIALTY CHEMICALS CORP. | 2001-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020107413-A1 | Organometallic monoacylarylphosphines | CBR1, NAF1, DHCR24 | NR5A1 49/4885TP53 3575/4885TSHR 984/4885 |
| US-20010031898-A1 | Organometallic monoacylarylphosphines | NAF1, DHCR24, CBR1 | NR5A1 133/4885TP53 3524/4885TSHR 1273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.