Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | ALPI | P09923 | 1/20 | 0.31 |
| ▸ | ALPG | P10696 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | CCR5 | P51681 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7171375 | 0.96 | KDM4E (0.42) | KDM4EMAPTNPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL7173060 | 0.96 | KDM4E (0.42) | KDM4EMAPTNPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL7173290 | 0.96 | KDM4E (0.42) | KDM4EMAPTNPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL7176802 | 0.96 | KDM4E (0.42) | KDM4EMAPTNPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL7179383 | 0.96 | KDM4E (0.42) | KDM4EMAPTNPC1SMN1; SMN2RAB9A | |
| Hydrochloric Acid SCHEMBL7173073 | 0.96 | KDM4E (0.42) | KDM4EMAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL14154741 | 0.96 | KDM4E (0.44) | KDM4EMAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL5176371 | 0.96 | KDM4E (0.44) | KDM4EMAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL28571116 | 0.96 | KDM4E (0.44) | KDM4EMAPTNPC1SMN1; SMN2RAB9A | |
| SCHEMBL5945715 | 0.83 | ALDH1A1 (0.50) | KDM4EMAPTNPC1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |