SCHEMBL7181544

SCHEMBL7181544

CC(C)(C)c1ccc2c(c1)C([Hf])c1cc(C(C)(C)C)ccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
NPC1 O15118 1/20 0.42
PLA2G1B P04054 1/20 0.42
NFKB1 P19838 1/20 0.42
CASP3 P42574 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SENP8 Q96LD8 1/20 0.42
SENP7 Q9BQF6 1/20 0.42
SENP6 Q9GZR1 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ATG4B Q9Y4P1 1/20 0.42
HPGD P15428 1/20 0.40
ALOX15 P16050 1/20 0.40
HSD17B10 Q99714 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37
MAPT P10636 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29713637 1.00 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
Hydrochloric Acid SCHEMBL20440943 0.98 ALDH1A1 (0.41) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL28502709 0.83 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL1538379 0.80 ALDH1A1 (0.44) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL30438243 0.80 ALDH1A1 (0.44) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL9754019 0.80 ALDH1A1 (0.44) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL30719677 0.80 DYRK1A (0.52) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL15458052 0.78 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL9754016 0.78 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3
SCHEMBL5080313 0.78 ALDH1A1 (0.42) ALDH1A1NPC1PLA2G1BNFKB1CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111630102-B Elastomeric terpolymer compositions for corner forming applications 埃克森美孚化学专利公司 2023-04-21 CN claimed
CN-111630102-A Elastomeric terpolymer compositions for corner molding applications 埃克森美孚化学专利公司 2020-09-04 CN claimed
CN-110662776-A Elastomeric compositions comprising EPDM and EPR 埃克森美孚化学专利公司 2020-01-07 CN claimed
CN-112805329-B Process for preparing polymer compositions with enhanced elasticity by employing VTP and HMP catalyst systems in parallel process 埃克森美孚化学专利公司 2024-02-02 CN disclosed
CN-117157333-A Ethylene copolymers with improved uniform molecular structure 博里利斯股份公司 2023-12-01 CN disclosed
CN-112352014-B Propylene-ethylene-diene terpolymer polyolefin additives for improved tire tread performance 埃克森美孚化学专利公司 2023-07-04 CN disclosed
CN-116234871-A Apparatus and method for producing in-line mixed polymers 博里利斯股份公司 2023-06-06 CN disclosed
CN-116209687-A Ethylene copolymers with improved melting and glass transition temperatures 博里利斯股份公司 2023-06-02 CN disclosed
CN-112004841-B Process for preparing high propylene content PEDM with low glass transition temperature using tetrahydroindacene based catalyst system 埃克森美孚化学专利公司 2023-05-26 CN disclosed
CN-111630102-B Elastomeric terpolymer compositions for corner forming applications 埃克森美孚化学专利公司 2023-04-21 CN disclosed
CN-111868117-B Method for preparing PEDM with high propylene content by using tetrahydroindacene base catalyst system 埃克森美孚化学专利公司 2023-04-21 CN disclosed
CN-112004841-A Method for preparing high propylene content PEDM with low glass transition temperature using tetrahydroindacene based catalyst system 埃克森美孚化学专利公司 2020-11-27 CN disclosed
CN-111868117-A Method for preparing high propylene content PEDM using tetrahydroindacene based catalyst system 埃克森美孚化学专利公司 2020-10-30 CN disclosed
CN-107922689-B Ethylene copolymers with in situ oil production 埃克森美孚化学专利公司 2020-09-08 CN disclosed
CN-101855249-B In-line process for producing plasticized polymers and plasticized polymer blends EXXONMOBIL RES & ENG CO 2013-02-13 CN disclosed
CN-101213244-B Method for preparing an article comprising a polymer concentrate EXXONMOBIL CHEM PATENTS INC 2011-04-20 CN disclosed
CN-101855249-A In-line process for producing plasticized polymers and plasticized polymer blends EXXONMOBIL RES & ENG CO 2010-10-06 CN disclosed
CN-101213244-A Method for preparing an article comprising a polymer concentrate EXXONMOBIL CHEM PATENTS INC (US) 2008-07-02 CN disclosed
EP-1349653-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION ExxonMobil Chemical Patents Inc. (US) 2003-10-08 EP disclosed
WO-2002036639-A2 FLUORINATED ZWITTERIONIC COCATALYST ACTIVATORS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-05-10 WO disclosed