Sugi Predict

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SCHEMBL7181691

SCHEMBL7181691

CCOC(C)Oc1ccc(PC(=O)c2c(C)cc(C)cc2C)cc1.[LiH]

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TSPO P30536 2/20 0.35
▸ ITGB1 P05556 1/20 0.34
▸ ITGA4 P13612 1/20 0.34
▸ MAPT P10636 2/20 0.33
▸ ALDH1A1 P00352 1/20 0.33
▸ GAA P10253 1/20 0.33
▸ SMN1; SMN2 Q16637 3/20 0.32
▸ FFAR4 Q5NUL3 1/20 0.32
▸ NPSR1 Q6W5P4 2/20 0.32
▸ HPGD P15428 2/20 0.32
▸ LMNA P02545 2/20 0.32
▸ KMT2A Q03164 2/20 0.32
▸ MEN1 O00255 1/20 0.32
▸ MCOLN3 Q8TDD5 1/20 0.32
▸ TDP1 Q9NUW8 1/20 0.31
▸ POLB P06746 1/20 0.31
▸ FFAR1 O14842 1/20 0.31
▸ L3MBTL1 Q9Y468 2/20 0.31
▸ PPARG P37231 1/20 0.31
▸ PPARD Q03181 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7180393 0.90 NR1H4 (0.35) SMN1; SMN2KMT2APPARGPPARDPPARA
SCHEMBL7185507 0.89 L3MBTL1 (0.34) MAPTSMN1; SMN2LMNAKMT2ATDP1
SCHEMBL7187865 0.88 SMN1; SMN2 (0.31) TSPOSMN1; SMN2LMNATDP1POLB
SCHEMBL7186827 0.87 FFAR4 (0.35) TSPOITGB1ITGA4MAPTALDH1A1
SCHEMBL7182650 0.85 ACACB (0.39) TSPOITGB1ITGA4MAPTALDH1A1
SCHEMBL7189074 0.85 ITGB1 (0.32) TSPOITGB1ITGA4SMN1; SMN2L3MBTL1
SCHEMBL7188695 0.84 FFAR4 (0.45) TSPOMAPTALDH1A1GAAFFAR4
Lithium SCHEMBL7181701 0.84 SMN1; SMN2 (0.34) TSPOITGB1ITGA4MAPTALDH1A1
SCHEMBL7175013 0.82 — —
SCHEMBL7186887 0.82 ALDH1A1 (0.41) ITGB1ITGA4MAPTALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 TSPO 3188/4885ITGB1 2786/4885ITGA4 3521/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 TSPO 2597/4885ITGB1 3321/4885ITGA4 3643/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.