Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 11/20 | 0.57 |
| ▸ | RAB9A | P51151 | 11/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.57 |
| ▸ | HPGD | P15428 | 9/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | CASP3 | P42574 | 3/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.57 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 6/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 6/20 | 0.46 |
| ▸ | RELA | Q04206 | 6/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181861 | 1.00 | NPC1 (0.57) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL29435921 | 0.91 | RAB9A (0.69) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL413260 | 0.91 | RAB9A (0.69) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL413259 | 0.91 | RAB9A (0.69) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL1857965 | 0.88 | RAB9A (0.58) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL2770602 | 0.88 | RAB9A (0.58) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL447887 | 0.87 | KDM4E (0.61) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL12304257 | 0.86 | NPC1 (0.62) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL28820725 | 0.85 | NPC1 (0.61) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 | |
| SCHEMBL15681800 | 0.84 | SMN1; SMN2 (0.70) | NPC1RAB9AKDM4EHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1325067-A1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEMICAL COMPANY (US) | 2003-07-09 | — | — | EP | claimed |
| WO-2002031035-A1 | MULTI-COMPONENT OPTICALLY BRIGHTENED POLYOLEFIN BLEND | EASTMAN CHEMICAL COMPANY (US) | 2002-04-18 | — | — | WO | claimed |