SCHEMBL447887

SCHEMBL447887

Cc1ccc2oc(-c3ccccc3/C=C/c3ccccc3-c3nc4cc(C)ccc4o3)nc2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 11/20 0.61
RAB9A P51151 11/20 0.61
NPC1 O15118 9/20 0.61
HPGD P15428 9/20 0.61
SMN1; SMN2 Q16637 9/20 0.61
CASP3 P42574 5/20 0.61
SENP7 Q9BQF6 5/20 0.61
SENP6 Q9GZR1 5/20 0.61
SENP8 Q96LD8 4/20 0.61
POLB P06746 1/20 0.61
ALDH1A1 P00352 10/20 0.56
HSD17B10 Q99714 9/20 0.56
TP53 P04637 6/20 0.56
MAPT P10636 6/20 0.52
TSHR P16473 2/20 0.52
NFKB1 P19838 3/20 0.51
NFKB2 Q00653 3/20 0.51
RELA Q04206 3/20 0.51
GAA P10253 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1857965 0.93 RAB9A (0.58) KDM4ERAB9ANPC1HPGDSMN1; SMN2
SCHEMBL2770602 0.93 RAB9A (0.58) KDM4ERAB9ANPC1HPGDSMN1; SMN2
SCHEMBL7181849 0.87 NPC1 (0.57) KDM4ERAB9ANPC1HPGDSMN1; SMN2
SCHEMBL7181861 0.87 NPC1 (0.57) KDM4ERAB9ANPC1HPGDSMN1; SMN2
SCHEMBL447889 0.84 RAB9A (0.53) KDM4ERAB9ANPC1HPGDSMN1; SMN2
SCHEMBL14148310 0.83 RAB9A (0.73) KDM4ERAB9ANPC1HPGDSMN1; SMN2
SCHEMBL13620844 0.81 KDM4E (0.69) KDM4ERAB9ANPC1HPGDSMN1; SMN2
SCHEMBL30498604 0.81 KDM4E (0.69) KDM4ERAB9ANPC1HPGDSMN1; SMN2
SCHEMBL22687002 0.81 TOP2A (0.53) KDM4ERAB9ANPC1HPGDSMN1; SMN2
SCHEMBL250148 0.81 TOP2A (0.53) KDM4ERAB9ANPC1HPGDSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9960371-B2 Organometallic complex, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-05-01 US disclosed
US-20170179409-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2017-06-22 US disclosed
US-8339039-B2 Light-emitting element including intermediate conductive layer having an electron-injection layer with an island-like structure SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2012-12-25 US disclosed
US-20120061653-A1 Light-Emitting Element and Display Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-15 US disclosed
US-6291151-B1 SILVER HALIDE LIGHT SENSITIVE ELEMENTS WITH YELLOW COUPLERS FUJI PHOTO FILM CO., LTD. (JP) 2001-09-18 US disclosed
EP-1028697-A2 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND HAIR CONDITIONING AGENTS THE PROCTER & GAMBLE COMPANY (US) 2000-08-23 EP disclosed
EP-1011616-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND NON-VOLATILE SOLVENTS THE PROCTER & GAMBLE COMPANY (US) 2000-06-28 EP disclosed
EP-1011614-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS WHICH PROVIDE UV PROTECTION THE PROCTER & GAMBLE COMPANY (US) 2000-06-28 EP disclosed
EP-1011615-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS WHICH ALTER HAIR COLORS THE PROCTER & GAMBLE COMPANY (US) 2000-06-28 EP disclosed
WO-1999013845-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS WHICH ALTER HAIR COLORS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013844-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS WHICH PROVIDE UV PROTECTION THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013822-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND POLYMERIC SUSPENDING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013846-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND SILICONE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013849-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND HIGH MELTING POINT COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013823-A2 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND HAIR CONDITIONING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013848-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND POLYMERIC SUSPENDING AGENTS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013833-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND CATIONIC COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013847-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND NON-VOLATILE SOLVENTS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed
WO-1999013832-A1 HAIR CARE COMPOSITIONS COMPRISING OPTICAL BRIGHTENERS AND WATER-INSOLUBLE HIGH MOLECULAR WEIGHT OILY COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1999-03-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170179409-A1 Organometallic Complex, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device C1S, CRY1, HEATR1 KDM4E 3712/4885RAB9A 3212/4885NPC1 3390/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.