SCHEMBL7181858

SCHEMBL7181858

C1=C(N2CCCC2)C=C(N2CCCC2)C1.[LiH]

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.33
HPGD P15428 1/20 0.33
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14420557 0.72
SCHEMBL14087874 0.67 MAPT (0.34) MAPTALDH1A1
SCHEMBL9637144 0.63
SCHEMBL21279450 0.63
SCHEMBL2328168 0.62 ALDH1A1 (0.36) ALDH1A1
SCHEMBL27772555 0.62
SCHEMBL6987370 0.61
SCHEMBL21163090 0.61
SCHEMBL13871982 0.60 MAPT (0.31) MAPTHPGD
SCHEMBL27772516 0.60 ALDH1A1 (0.34) MAPTHPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6617407-B1 Olefin polymerization catalyst components. THE DOW CHEMICAL COMPANY 2003-09-09 US disclosed
EP-1177198-B1 BIS(N,N-DIHYDROCARBYLAMINO)- SUBSTITUTED CYCLOPENTADIENES AND METAL COMPLEXES THEREOF DOW GLOBAL TECHNOLOGIES INC (US) 2002-11-20 EP disclosed