SCHEMBL13871982

SCHEMBL13871982

C1=CCC(N2CCCC2)=CC1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.31
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14420557 0.79
SCHEMBL18944069 0.62 HPGD (0.32) HPGD
SCHEMBL7182131 0.62 MAPT (0.34) MAPTHPGD
SCHEMBL7181858 0.60 MAPT (0.33) MAPTHPGD
SCHEMBL497532 0.60 MAPT (0.38) MAPTHPGD
SCHEMBL10482676 0.60 ALDH1A1 (0.37) MAPTHPGD
SCHEMBL21088278 0.60 GAA (0.33) MAPT
SCHEMBL23661070 0.59 MAPT (0.37) MAPTHPGD
SCHEMBL497034 0.59 MAPT (0.37) MAPTHPGD
SCHEMBL368150 0.59 MAPT (0.37) MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090099248-A1 INHIBITORS OF D-AMINO ACID OXIDASE SEPRACOR INC. (US) 2009-04-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090099248-A1 INHIBITORS OF D-AMINO ACID OXIDASE DDO, DAO, ACHE MAPT 444/4885HPGD 624/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.