Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | IKBKB | O14920 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7189481 | 0.90 | TSHR (0.46) | KIF11TSHRMAPK1NR2E1ALDH1A1 | |
| SCHEMBL27153247 | 0.86 | ALDH1A1 (0.43) | KIF11TSHRMAPK1HPGDESR1 | |
| SCHEMBL10631366 | 0.85 | ALDH1A1 (0.46) | KIF11TSHRMAPK1HPGDESR1 | |
| SCHEMBL7192380 | 0.81 | TSHR (0.66) | KIF11TSHRMAPK1MAOBPTGS1 | |
| SCHEMBL7186572 | 0.81 | FFAR4 (0.41) | KIF11TSHRMAPK1NR2E1HPGD | |
| SCHEMBL7183524 | 0.79 | TSHR (0.47) | KIF11TSHRMAPK1NR2E1HPGD | |
| SCHEMBL130383 | 0.78 | TSHR (0.56) | KIF11TSHRMAPK1NR2E1ALDH1A1 | |
| SCHEMBL108051 | 0.78 | CYP3A4 (0.52) | KIF11TSHRMAPK1HPGDESR1 | |
| SCHEMBL1729158 | 0.78 | CYP3A4 (0.52) | KIF11TSHRMAPK1HPGDESR1 | |
| SCHEMBL126726 | 0.78 | CYP3A4 (0.52) | KIF11TSHRMAPK1HPGDESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064235-A1 | Optical members made of polymide resins | MITSUI CHEMICALS, INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1237015-A1 | OPTICAL MEMBERS MADE OF POLYIMIDE RESINS | Mitsui Chemicals, Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |