Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 2/20 | 0.39 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.35 |
| ▸ | TACR1 | P25103 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.34 |
| ▸ | ITGAV | P06756 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7182065 | 0.90 | KIF11 (0.50) | TSHRMAPK1NR2E1IKBKBKIF11 | |
| SCHEMBL130383 | 0.87 | TSHR (0.56) | TSHRMAPK1NR2E1IKBKBIDO1 | |
| SCHEMBL7192380 | 0.87 | TSHR (0.66) | TSHRMAPK1NR2E1IKBKBKIF11 | |
| SCHEMBL12024580 | 0.86 | TSHR (0.46) | TSHRMAPK1NR2E1IKBKBIDO1 | |
| SCHEMBL545803 | 0.86 | TSHR (0.46) | TSHRMAPK1NR2E1IKBKBIDO1 | |
| SCHEMBL23113676 | 0.86 | TSHR (0.46) | TSHRMAPK1NR2E1IKBKBIDO1 | |
| SCHEMBL14200010 | 0.86 | MAPK1 (0.46) | TSHRMAPK1NR2E1IKBKBIDO1 | |
| Iodide SCHEMBL31550893 | 0.85 | TSHR (0.54) | TSHRMAPK1NR2E1IKBKBIDO1 | |
| SCHEMBL7186572 | 0.82 | FFAR4 (0.41) | TSHRMAPK1NR2E1IKBKBKIF11 | |
| SCHEMBL545622 | 0.82 | TSHR (0.43) | TSHRMAPK1NR2E1IKBKBIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030064235-A1 | Optical members made of polymide resins | MITSUI CHEMICALS, INC. (JP) | 2003-04-03 | — | — | US | disclosed |
| EP-1237015-A1 | OPTICAL MEMBERS MADE OF POLYIMIDE RESINS | Mitsui Chemicals, Inc. (JP) | 2002-09-04 | — | — | EP | disclosed |