Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 19/20 | 1.00 |
| ▸ | MMP1 | P03956 | 5/20 | 0.66 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | MMP7 | P09237 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181803 | 0.88 | MMP13 (0.79) | MMP13MMP1MMP2MMP3MMP9 | |
| SCHEMBL7181809 | 0.88 | MMP13 (0.79) | MMP13MMP1MMP2MMP3MMP9 | |
| SCHEMBL7301940 | 0.86 | MMP13 (0.76) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL7181926 | 0.86 | MMP13 (0.75) | MMP13MMP1MMP2MMP7MMP9 | |
| Hydrochloric Acid SCHEMBL7302619 | 0.85 | MMP13 (0.74) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL7308056 | 0.84 | MMP13 (1.00) | MMP13MMP1 | |
| SCHEMBL7308069 | 0.84 | MMP13 (1.00) | MMP13MMP1 | |
| SCHEMBL7302708 | 0.83 | MMP13 (0.73) | MMP13MMP1MMP2MMP3MMP7 | |
| SCHEMBL7186097 | 0.82 | MMP13 (1.00) | MMP13MMP1MMP2MMP3MMP9 | |
| Hydrochloric Acid SCHEMBL7307675 | 0.82 | MMP13 (0.71) | MMP13MMP1MMP2MMP3MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583299-B1 | Matrix metalloprotease inhibitors; nonsuppression of tumor necrosis factor production | G.D. SEARLE & CO. | 2003-06-24 | — | — | US | disclosed |