SCHEMBL718219

SCHEMBL718219

O=C1C=CC(=O)N1c1cccc2c1ccc1ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.62
TLR9 Q9NR96 1/20 0.55
CYP1A2 P05177 2/20 0.51
CYP2C9 P11712 2/20 0.51
CYP2C19 P33261 2/20 0.51
POLB P06746 1/20 0.51
HPRT1 P00492 1/20 0.50
MGLL Q99685 9/20 0.47
PAX8 Q06710 1/20 0.47
ALDH1A1 P00352 2/20 0.46
HPGD P15428 2/20 0.46
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
HSD17B10 Q99714 1/20 0.46
ELANE P08246 1/20 0.45
MEN1 O00255 1/20 0.45
USP2 O75604 1/20 0.45
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.45
CYP2D6 P10635 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29386767 0.89 TLR9 (0.64) TDP1TLR9POLBMGLLALDH1A1
SCHEMBL152339 0.89 TLR9 (0.64) TDP1TLR9POLBMGLLALDH1A1
SCHEMBL9614311 0.88 CYP1A2 (0.63) TDP1TLR9CYP1A2CYP2C9CYP2C19
SCHEMBL31179969 0.84 TLR9 (0.68) TDP1TLR9POLBMGLLALDH1A1
SCHEMBL3277562 0.84 TLR9 (0.68) TDP1TLR9POLBMGLLALDH1A1
SCHEMBL31180023 0.80 TLR9 (0.68) TDP1TLR9MGLLALDH1A1HPGD
SCHEMBL5077484 0.80 TLR9 (0.68) TDP1TLR9MGLLALDH1A1HPGD
SCHEMBL9172433 0.79 MGLL (0.58) TDP1TLR9POLBMGLLALDH1A1
SCHEMBL31179984 0.77 HSP90AA1 (0.61) TLR9POLBMGLLALDH1A1PKM
SCHEMBL31179946 0.77 HSP90AA1 (0.61) TLR9POLBMGLLALDH1A1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9777092-B2 Ionomer resin composition, optical film, polarizing plate, and liquid crystal display apparatus JX NIPPON OIL & ENERGY CORPORATION (JP) 2017-10-03 US disclosed
US-20160369023-A1 IONOMER RESIN COMPOSITION, OPTICAL FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY APPARATUS JX NIPPON OIL & ENERGY CORPORATION (JP) 2016-12-22 US disclosed
US-20160282519-A1 ACRYLIC COPOLYMER, OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE UNIV KEIO (JP) 2016-09-29 US disclosed
US-20150369963-A1 ACRYLIC COPOLYMER, OPTICAL FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE KEIO UNIVERSITY (JP) 2015-12-24 US disclosed
US-9150414-B2 Nanocomposite and dispersion comprising the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2015-10-06 US disclosed
US-20120053288-A1 NANOCOMPOSITE AND DISPERSION COMPRISING THE SAME KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2012-03-01 US disclosed