Sugi Predict

Sugi Predict / Compounds / SCHEMBL7182347

SCHEMBL7182347

SCHEMBL7182347

Cc1cc(C(C)(C)C)cc(C)c1C(=O)Pc1ccc(OCCC(C)C)cc1OCCC(C)C.[LiH]

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.39
▸ EPHX2 P34913 1/20 0.38
▸ ESR1 P03372 1/20 0.36
▸ NR1I2 O75469 1/20 0.36
▸ PDK2 Q15119 1/20 0.36
▸ PPARG P37231 1/20 0.35
▸ PPARD Q03181 1/20 0.35
▸ PPARA Q07869 1/20 0.35
▸ S1PR1 P21453 1/20 0.35
▸ S1PR5 Q9H228 1/20 0.35
▸ TP53 P04637 1/20 0.35
▸ SMN1; SMN2 Q16637 1/20 0.35
▸ HTT P42858 2/20 0.34
▸ TDP1 Q9NUW8 1/20 0.34
▸ GAA P10253 1/20 0.34
▸ MMP2 P08253 1/20 0.33
▸ MMP13 P45452 1/20 0.33
▸ NR1H4 Q96RI1 2/20 0.33
▸ GALR3 O60755 1/20 0.33
▸ HSP90AA1 P07900 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7188686 0.91 MAPK1 (0.40) MAPK1EPHX2ESR1NR1I2PDK2
SCHEMBL7182736 0.90 MAPK1 (0.41) MAPK1EPHX2ESR1PDK2S1PR1
SCHEMBL7188997 0.88 MAPT (0.38) NR1I2PPARGPPARDPPARASMN1; SMN2
SCHEMBL7184637 0.88 MAPK1 (0.41) MAPK1EPHX2ESR1PDK2PPARG
SCHEMBL7183681 0.88 PPARG (0.39) ESR1NR1I2PPARGPPARDPPARA
SCHEMBL7185499 0.87 CACNA1H (0.35) NR1I2PPARGPPARDPPARAHTT
SCHEMBL7177986 0.87 FOS (0.36) PDK2PPARGPPARDPPARA
SCHEMBL7179801 0.86 MAPK1 (0.40) MAPK1EPHX2ESR1PDK2S1PR1
SCHEMBL7179784 0.86 ITGB1 (0.39) ESR1PPARGPPARDPPARAS1PR1
Lithium SCHEMBL7183689 0.86 PPARG (0.37) ESR1NR1I2PPARGPPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 MAPK1 1801/4885EPHX2 2476/4885ESR1 3736/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 MAPK1 2710/4885EPHX2 2048/4885ESR1 3621/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.