Sugi Predict

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SCHEMBL7188686

SCHEMBL7188686

Cc1cc(OCCC(C)C)ccc1PC(=O)c1c(C)cc(C(C)(C)C)cc1C.[LiH]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPK1 P28482 1/20 0.40
▸ EPHX2 P34913 1/20 0.39
▸ PDK2 Q15119 1/20 0.37
▸ TP53 P04637 2/20 0.36
▸ S1PR1 P21453 1/20 0.36
▸ S1PR5 Q9H228 1/20 0.36
▸ SMN1; SMN2 Q16637 1/20 0.36
▸ PPARG P37231 1/20 0.36
▸ PPARD Q03181 1/20 0.36
▸ PPARA Q07869 1/20 0.36
▸ TDP1 Q9NUW8 1/20 0.35
▸ GAA P10253 1/20 0.35
▸ HTT P42858 1/20 0.35
▸ NR1H4 Q96RI1 2/20 0.34
▸ GALR3 O60755 1/20 0.34
▸ HSP90AA1 P07900 1/20 0.34
▸ MMP2 P08253 1/20 0.34
▸ MMP13 P45452 1/20 0.34
▸ NR1I2 O75469 1/20 0.34
▸ ESR1 P03372 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7182347 0.91 MAPK1 (0.39) MAPK1EPHX2PDK2TP53S1PR1
SCHEMBL7187971 0.90 MAPK1 (0.43) MAPK1EPHX2PDK2TP53S1PR1
SCHEMBL7179629 0.89 XDH (0.37) PDK2TP53SMN1; SMN2PPARGPPARD
SCHEMBL7187020 0.87 MAPK1 (0.43) MAPK1EPHX2PDK2TP53S1PR1
SCHEMBL7175802 0.87 MAPT (0.39) SMN1; SMN2PPARGPPARDPPARAGAA
SCHEMBL7179994 0.87 THRB (0.39) SMN1; SMN2PPARGPPARDPPARATHRB
SCHEMBL7180470 0.86 MAPK1 (0.45) MAPK1EPHX2PDK2TP53S1PR1
SCHEMBL7184824 0.86 KDM4E (0.37) EPHX2SMN1; SMN2PPARGPPARDPPARA
SCHEMBL7182258 0.85 MAPK1 (0.41) MAPK1EPHX2PDK2TP53S1PR1
SCHEMBL7177466 0.85 THRB (0.42) TP53S1PR1S1PR5THRBTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6579663-B2 Chemical intermediates such as lithium 2,6-dimethylbenzoyl phenylphosphine for preparation of acylphosphines, acylphosphine oxides or acylphosphine sulfides CIBA SPECIALTY CHEMICALS CORPORATION 2003-06-17 — — US disclosed
US-20020107413-A1 Organometallic monoacylarylphosphines WOLF JEAN-PIERRE (CH) 2002-08-08 — — US disclosed
US-6399805-B2 SUCH AS LITHIUM 2,6-DIMETHYLBENZOYLPHENYLPHOSPHINE, USE AS PHOTOINITIATORS IN PHOTOCURABLE COMPOSITIONS SUCH AS FOR PHOTOGRAPHIC PRODUCTION OF RELIEF IMAGES CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-04 — — US disclosed
US-20010031898-A1 Organometallic monoacylarylphosphines CIBA SPECIALTY CHEMICALS CORP. 2001-10-18 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020107413-A1 Organometallic monoacylarylphosphines CBR1, NAF1, DHCR24 MAPK1 1801/4885EPHX2 2476/4885PDK2 3391/4885
US-20010031898-A1 Organometallic monoacylarylphosphines NAF1, DHCR24, CBR1 MAPK1 2710/4885EPHX2 2048/4885PDK2 3516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.