Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BPTF | Q12830 | 1/20 | 0.53 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.52 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 3/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10178032 | 0.89 | BPTF (0.67) | BPTFMBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL10177792 | 0.89 | BPTF (0.67) | BPTFMBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL9967187 | 0.89 | BPTF (0.67) | BPTFMBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL4703341 | 0.85 | CYP2D6 (0.50) | BPTFMBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL14270564 | 0.83 | DRD2 (0.59) | CYP2D6SLC6A2SLC6A4CHRNA7SIGMAR1 | |
| SCHEMBL15651158 | 0.82 | MAPT (0.52) | BPTFL3MBTL3L3MBTL1CXCR4LMNA | |
| SCHEMBL3389633 | 0.82 | CYP2D6 (0.56) | BPTFMBTD1L3MBTL3L3MBTL1HRH3 | |
| SCHEMBL13182959 | 0.81 | ADRB1 (0.48) | BPTFL3MBTL3L3MBTL1CXCR4ADRB1 | |
| SCHEMBL785122 | 0.81 | CHKA (0.53) | BPTFHRH3NCF1 | |
| SCHEMBL16394309 | 0.81 | SLC6A2 (0.49) | BPTFL3MBTL3L3MBTL1CXCR4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10669274-B2 | Azaphenalene-3-one derivative, preparation method therefor, and application therof | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2020-06-02 | — | — | US | claimed |
| US-20200031828-A1 | AZAPHENALENE-3-ONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEROF | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2020-01-30 | — | — | US | claimed |
| EP-4653424-A1 | PYRIDAZINONE PARP INHIBITOR, AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | China Pharmaceutical University (CN) | 2025-11-26 | — | — | EP | disclosed |
| CN-118388414-A | Pyridazinone compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-07-26 | — | — | CN | disclosed |
| WO-2024152855-A1 | PYRIDAZINONE PARP INHIBITOR, AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国药科大学 | 2024-07-25 | — | — | WO | disclosed |
| CN-111808017-B | Nitrogen-containing heterocyclic compound, and preparation method and application thereof | 国家纳米科学中心 | 2023-11-28 | — | — | CN | disclosed |
| US-10669274-B2 | Azaphenalene-3-one derivative, preparation method therefor, and application therof | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2020-06-02 | — | — | US | disclosed |
| US-10669274-B2 | Azaphenalene-3-one derivative, preparation method therefor, and application therof | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2020-06-02 | — | — | US | disclosed |
| US-20200031828-A1 | AZAPHENALENE-3-ONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEROF | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2020-01-30 | — | — | US | disclosed |
| US-20200031828-A1 | AZAPHENALENE-3-ONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEROF | SUZHOU KANGRUN PHARMACEUTICALS INC. (CN) | 2020-01-30 | — | — | US | disclosed |
| WO-2019179362-A1 | AMIDINE AND GUANIDINE DERIVATIVES, PREPARATION METHOD THEREFOR AND MEDICAL USES THEREOF | 四川科伦博泰生物医药股份有限公司 | 2019-09-26 | — | — | WO | disclosed |
| EP-1301464-A1 | BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | Boehringer Ingelheim Pharma KG (DE) | 2003-04-16 | — | — | EP | disclosed |
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-03-14 | — | — | US | disclosed |
| WO-2002004403-A1 | BIPHENYLCARBOXYLIC ACID AMIDES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-01-17 | — | — | WO | disclosed |
| CN-1052723-C | Bicyclic aromatic compounds as therapeutic agents | KNOLL AG (DE) | 2000-05-24 | — | — | CN | disclosed |
| EP-0717739-B1 | 1,4-Benzodioxane derivatives having affinity for D2 receptors and utility in the treatment of psychoses | KNOLL AG (DE) | 2000-03-29 | — | — | EP | disclosed |
| US-5767116-A | TREATING PSYCHOSES | KNOLL ATKIENGESELLSCHAFT (DE) | 1998-06-16 | — | — | US | disclosed |
| CN-1133043-A | Bicyclic aromatic compounds as therapeutic agents | BOOTS CO PLC (DE) | 1996-10-09 | — | — | CN | disclosed |
| EP-0717739-A1 | BICYCLIC AROMATIC COMPOUNDS AS THERAPEUTIC AGENTS | Knoll AG (DE) | 1996-06-26 | — | — | EP | disclosed |
| WO-1995007274-A1 | BICYCLIC AROMATIC COMPOUNDS AS THERAPEUTIC AGENTS | KNOLL AG (DE) | 1995-03-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020032238-A1 | Biphenylcarboxylic acid amides, the preparation thereof and the use thereof as medicaments | MTTP, CETP, FABP1 | BPTF 490/4885MBTD1 487/4885L3MBTL3 4711/4885 |
| US-20200031828-A1 | AZAPHENALENE-3-ONE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEROF | PARP1, PARP11, PARP8 | BPTF 85/4885MBTD1 1783/4885L3MBTL3 4565/4885 |
| US-10669274-B2 | Azaphenalene-3-one derivative, preparation method therefor, and application therof | PARP1, PARP11, PARP8 | BPTF 85/4885MBTD1 1783/4885L3MBTL3 4565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.