Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7181457 | 0.97 | LMNA (0.40) | LMNAALDH1A1MAPK1THRBTSHR | |
| Hydrochloric Acid SCHEMBL7182723 | 0.97 | LMNA (0.40) | LMNAALDH1A1MAPK1THRBTSHR | |
| Hydrochloric Acid SCHEMBL7175587 | 0.97 | LMNA (0.40) | LMNAALDH1A1MAPK1THRBTSHR | |
| Hydrochloric Acid SCHEMBL7174259 | 0.97 | LMNA (0.40) | LMNAALDH1A1MAPK1THRBTSHR | |
| Hydrochloric Acid SCHEMBL7173377 | 0.97 | LMNA (0.40) | LMNAALDH1A1MAPK1THRBTSHR | |
| Hydrochloric Acid SCHEMBL7176669 | 0.97 | LMNA (0.40) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11822342 | 0.78 | LMNA (0.44) | LMNAALDH1A1MAPK1THRBTSHR | |
| SCHEMBL11717108 | 0.77 | LMNA (0.41) | LMNAALDH1A1MAPK1THRBTSHR | |
| Hydrochloric Acid SCHEMBL7183205 | 0.75 | KDM4E (0.38) | LMNAMAPK1THRBSMN1; SMN2ATM | |
| SCHEMBL11716547 | 0.75 | LMNA (0.41) | LMNAALDH1A1MAPK1THRBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1367069-A1 | Process for homo-or copolymerization of conjugated diens | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-12-03 | — | — | EP | disclosed |