Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7044868 | 0.93 | LMNA (0.37) | KMT2ALMNAMAPTTSHRSMN1; SMN2 | |
| SCHEMBL7047004 | 0.88 | MAPT (0.34) | KMT2ALMNAMAPTTSHRSMN1; SMN2 | |
| SCHEMBL6464160 | 0.79 | LMNA (0.39) | KMT2ALMNAMAPTTSHRSMN1; SMN2 | |
| SCHEMBL7048374 | 0.78 | POLB (0.38) | EPHX2 | |
| SCHEMBL7045897 | 0.76 | EPHX2 (0.38) | KMT2ATSHRSMN1; SMN2EPHX2NPC1 | |
| SCHEMBL6463625 | 0.75 | KCNJ6 (0.36) | KMT2ASMN1; SMN2ACACBEPHX2NPC1 | |
| SCHEMBL6467251 | 0.74 | CTSS (0.46) | CTSSFAAH | |
| SCHEMBL6061692 | 0.74 | CTSS (0.41) | KMT2ALMNASMN1; SMN2HTTCTSS | |
| SCHEMBL7049550 | 0.73 | DAGLA (0.46) | LMNAMAPTTSHRSMN1; SMN2HTT | |
| SCHEMBL7045443 | 0.73 | MEN1 (0.45) | KMT2ALMNAMAPTTSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6576630-B1 | Alkanoyl substituted benzooxazoles or naphthooxazoles | AXYS PHARMACEUTICALS, INC. | 2003-06-10 | — | — | US | disclosed |